Introduction: There is paucity of data on the effectiveness and safety of tofacitinib among elderly patients with ulcerative colitis (UC).
Methods: Through a retrospective cohort study among the US National Veterans Affairs Healthcare System, we evaluated effectiveness among the elderly (≥65) and young (<65) patients with UC initiated on tofacitinib.
Results: Among 158 patients (53 elderly, 105 young), effectiveness at 12 months was 50.94% in the elderly and 33.33% in the young ( P = 0.032).
Discussion: In a nationwide cohort of patients with UC initiating tofacitinib, effectiveness was seen in half of the elderly patients.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11288386 | PMC |
| http://dx.doi.org/10.14309/ajg.0000000000002761 | DOI Listing |
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