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Fostering healthy cognitive ageing in people living with HIV.
Lancet HIV
January 2025
MAP Centre for Urban Health Solutions, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada; Department of Psychiatry, University of Toronto, Toronto, ON, Canada.
Prevalence and incidence of HIV among people aged 50 years and older continue to rise worldwide, generating increasing awareness among care providers, scientists, and the HIV community about the importance of brain health in older adults with HIV. Many age-related factors that adversely affect brain health can occur earlier and more often among people with HIV, including epigenetic ageing, chronic medical conditions (eg, cardiovascular disease), and age-related syndromes (eg, frailty). Extensive dialogue between HIV community leaders, health-care providers, and scientists has led to the development of a multidimensional response strategy to protect and enhance brain health in people ageing with HIV that spans across public health, clinical spaces, and research spaces.
View Article and Find Full Text PDFCurrent Challenges, Solutions, and Novel Directions in Research and Clinical Care: Proceedings From the 14th Annual International Workshop on HIV and Aging.
J Gerontol A Biol Sci Med Sci
December 2024
Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Article Synopsis
- - The 14th International Workshop on HIV and Aging, held on October 26-27, 2023, focused on improving health span for people living with HIV (PWH) by exploring issues related to aging and comorbid conditions.
- - Key topics included the biology and treatment of sarcopenia, long-acting antiretroviral therapy (ART), and complications related to the central nervous system, along with mental health and social factors.
- - Presentations emphasized the need for prioritizing mental health care, addressing loneliness, and conducting research on resilience among PWH to tackle ongoing challenges.
'We are fragile, but we are strong': A qualitative study of perspectives, experiences and priority outcomes for people living with HIV and frailty.
HIV Med
October 2024
King's College London, Cicely Saunders Institute of Palliative Care, Policy & Rehabilitation, London, UK.
Article Synopsis
- The study focuses on how living with both HIV and frailty affects older individuals, spotlighting the need for chronic disease management as the HIV population ages.
- Through in-depth interviews with 24 participants from a UK HIV clinic, it was found that frailty limits physical, psychological, and social wellbeing, and while the term 'frail' was generally accepted, participants suggested the need for clearer definitions specific to HIV.
- The conclusion emphasizes the importance of healthcare professionals being honest yet sensitive when discussing frailty, advocating for a holistic approach to care that prioritizes maintaining independence and addressing the broader impacts of frailty.
Frailty and HIV-associated neurocognitive disorder are only modestly associated.
AIDS
April 2024
School of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
Objective: Frailty measures vary widely and the optimal measure for predicting HIV-associated neurocognitive disorders (HAND) is unclear.
Design: A study was conducted to examine the clinical utility of three widely used frailty measures in identifying HIV-associated neurocognitive disorders.
Methods: The study involved 284 people with HIV (PWH) at least 50 years enrolled at UC San Diego's HIV Neurobehavioral Research Program.
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