Objective: Small series and individual cases of penile soft tissue tumours are reported in the literature: these are rare tumours that represent less than 5% of all penile tumours.
Methods: Penile soft tissue tumours were collected from the archive of the Department of Pathology at the Istituto Nazionale dei Tumori of Milan between January 1990 and October 2021. All available medical records were retrieved and reviewed to obtain clinical information.
Results: Our series refers to the 30-year experience of highlighting the heterogeneity in the presentation and microscopic features of these rare sarcomas. 18 penile soft tissue tumours are described, 4 benign and 14 malignant. The mean age at diagnosis was 58.2 years (range 24-96 years) and 53.6 years among malignancies (range 24-89). The most frequent histotype was Kaposi's sarcoma (nr = 4) and very unusual histotypes were observed, namely low-grade fibromyxoid sarcoma, synovial sarcoma, proximal type epithelioid sarcoma and the first reported case of dedifferentiated liposarcoma of the penis.
Conclusions: Among sarcomas of the genitourinary tract, tumours of the soft tissues of the penis are the rarest. Penile sarcomas can present at a young age. Kaposi's sarcoma in HIV-negative patients has a favorable outcome, while deep sarcomas have an aggressive behavior and poor prognosis.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10938274 | PMC |
| http://dx.doi.org/10.32074/1591-951X-953 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Provisional Prosthetic Outcome when Using Photogrammetry for Complete Arch Oral Implants: A Report of 111 Patient Treatments.
Oral Maxillofac Surg Clin North Am
December 2024
Private Practice, Brooklyn, NY, USA.
Complete arch oral implant treatment using photogrammetry was studied in 77 patients with 111 arches focusing on digitization of clinical records and optimization of the provisional. The aim of the study was to test the hypothesis that patient satisfaction with the provisional prosthesis during the first 4 months of care determined workflow efficiency and success. Digitization of 8 clinical records was done including centric relation, vertical dimension, esthetics, occlusion, inter-arch space, abutment selection, abutment capture, and soft tissue scan.
View Article and Find Full Text PDFFree medial sural artery perforator flap for soft tissue defects in the hand: a cadaver study.
Hand Surg Rehabil
December 2024
Department of Hand Surgery, Plastic and Reconstructive Surgery, Centre Chirurgical Émile Gallé, Nancy University Hospital, 49 rue Hermite, 54000 Nancy, France; Department of Anatomy, Faculty of Medicine, University of Lorraine, 9 Av. de la Forêt de Haye, 54500 Vandœuvre-lès-Nancy, France. Electronic address:
We carried out a cadaver study using 10 fresh-frozen adult legs and hands to explore technical feasibility and reproducibility of the free Medial Sural Artery Perforator flap and its applicability for covering soft tissue defects in the hand. A mean of 2 cutaneous perforators (1-4) were found. Each flap had a pedicle composed of a main perforator that arose from the medial sural artery.
View Article and Find Full Text PDFVerification imaging in prostate MR-only radiotherapy: Are fiducial markers necessary?
Radiography (Lond)
December 2024
Newcastle Upon Tyne Hospitals NHS Foundation Trust, Northern Centre for Cancer Care, Newcastle Upon Tyne, United Kingdom; Newcastle University, Translational and Clinical Research Institute, Newcastle Upon Tyne, United Kingdom.
Purpose/objective: MR-only radiotherapy planning exploits the benefits of MRI soft-tissue delineation, whilst negating the registration inaccuracies caused by MRI CT fusion. Fiducial markers have conventionally been used in prostate radiotherapy to reduce on-treatment image matching variability. However, this is an invasive procedure for the patient, and presents technical difficulties in an MR-only pathway as fiducial markers are difficult to visualise on MRI.
View Article and Find Full Text PDFAnalysis of posterior hip joint impingement about developmental dysplasia of the hip after total hip arthroplasty.
Clin Biomech (Bristol)
December 2024
Department of Orthopedic Surgery, Hiroshima University Hospital Graduate School of Biomedical and Health Sciences, Hiroshima City, Hiroshima Prefecture, Japan.
Background: Total hip arthroplasty is the preferred treatment for advanced hip osteoarthritis, yet complications like hip dislocation (0.2 %-10 %) persist due to factors such as implant design, positioning, surgical technique, and patient-specific conditions. Impingement between prosthetic components or the acetabulum and proximal femur is a primary cause of instability.
View Article and Find Full Text PDFUpdates on the MR safety guidelines - Essentials for radiologists.
Clin Imaging
December 2024
Department of Radiology, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, USA. Electronic address:
Magnetic Resonance Imaging (MRI) is a sophisticated diagnostic tool that utilizes the magnetic properties of biological tissue to generate detailed images of internal structures without the use of ionizing radiation. Despite its benefits in providing high-contrast images of soft tissues, the strong magnetic fields used in MRI present a unique safety challenge. Increasing MRI-related accidents and the prevalence of patients with metallic implants in recent years underscore the critical need for stringent MR safety protocols.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!