Clinical narratives commonly use acronyms without explicitly defining their long forms. This makes it difficult to automatically interpret their sense as acronyms tend to be highly ambiguous. Supervised learning approaches to their disambiguation in the clinical domain are hindered by issues associated with patient privacy and manual annotation, which limit the size and diversity of training data. In this study, we demonstrate how scientific abstracts can be utilised to overcome these issues by creating a large automatically annotated dataset of artificially simulated global acronyms. A neural network trained on such a dataset achieved the F1-score of 95% on disambiguation of acronym mentions in scientific abstracts. This network was integrated with multi-word term recognition to extract a sense inventory of acronyms from a corpus of clinical narratives on the fly. Acronym sense extraction achieved the F1-score of 74% on a corpus of radiology reports. In clinical practice, the suggested approach can be used to facilitate development of institution-specific inventories.
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http://dx.doi.org/10.3389/fdgth.2024.1282043 | DOI Listing |
Curr Opin Crit Care
January 2025
Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS).
Purpose Of Review: This narrative review discusses the mechanisms connecting gut dysbiosis to adverse clinical outcomes in critically ill patients and explores potential therapeutic strategies.
Recent Findings: In recent years, the study of microbiota in ICUs has gained attention because of its potential effects on patient outcomes. Critically ill patients often face severe conditions, which can compromise their immune systems and lead to opportunistic infections from bacteria typically harmless to healthy individuals.
J Med Humanit
January 2025
The University of North Carolina School of Medicine, 321 Columbia St, Chapel Hill, NC, 27514, USA.
A growing body of literature explores the intersection of eating disorders and identity formation-an entanglement that makes eating disorders particularly challenging to treat. Narrative medicine is a discipline of the health humanities that is interested in bearing witness to patients' stories with a closeness and rigor that enhances clinical care. The pedagogy of the field is the narrative medicine workshop, which mobilizes close-reading of works of art and reflective writing to improve our understanding of Self and Other.
View Article and Find Full Text PDFCurr Pain Headache Rep
January 2025
Department of Pain Medicine, Division of Anesthesiology, Critical Care & Pain Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Purpose Of Review: Quickly referenceable, streamlined, algorithmic approaches for advanced pain management are lacking for patients, trainees, non-pain specialists, and interventional specialists. This manuscript aims to address this gap by proposing a comprehensive, evidence-based algorithm for managing neuropathic, nociceptive, and cancer-associated pain. Such an algorithm is crucial for pain medicine education, offering a structured approach for patient care refractory to conservative management.
View Article and Find Full Text PDFReumatismo
January 2025
Unit of Dermatology, Department of Medicine and Aging Science, G. d'Annunzio University, Chieti.
Objective: Psoriatic arthritis (PsA) can be treated with biological drugs targeting IL-17A, such as secukinumab, with good responses and long-term positive outcomes in clinical studies.
Methods: An observational study was conducted on adult subjects with PsA and comorbidities, treated with secukinumab after prior therapy with conventional disease-modifying anti-rheumatic drugs or biological agents that were discontinued due to lack of efficacy or adverse drug reactions. Patients were followed up with clinical visits at 3, 6, 9, and 12 months and evaluated for disease activity, pain, and quality of life, with respect to values recorded at baseline.
Cochrane Database Syst Rev
January 2025
Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Background: People from lower socioeconomic groups are more likely to smoke and less likely to succeed in achieving abstinence, making tobacco smoking a leading driver of health inequalities. Contextual factors affecting subpopulations may moderate the efficacy of individual-level smoking cessation interventions. It is not known whether any intervention performs differently across socioeconomically-diverse populations and contexts.
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