AI Article Synopsis
- - The Grand Magal of Touba (GMT) poses risks of infection for pilgrims, with a study conducted examining the circulation of resistant bacteria among attendees between 2018 and 2021.
- - Out of the pilgrims studied, 31.4% acquired pathogenic bacteria, predominantly Escherichia coli, and 36.2% gained resistance genes, indicating a concerning trend in antibiotic resistance.
- - The findings suggest that pilgrims are at increased risk for acquiring specific resistance genes, particularly CTX-M A, and highlight the need for future surveillance of resistant bacteria and related infections in such gatherings.
Article Abstract
Background: The Grand Magal of Touba (GMT) associates with risks of infection, but no study on the circulation of resistant bacteria has yet been conducted.
Materials And Methods: qPCR was performed on rectal samples from GMT pilgrims between 2018 and 2021, before and after their participation in the gathering. Rectal samples from between 2018 and 2020 were also cultured on specific media, and antibiotic susceptibility testing was performed.
Results: Forty-one of the 296 (13.8%) pilgrims had at least one gastrointestinal symptom and 91/290 (31.4%) acquired pathogenic bacteria, mostly Escherichia coli. A total of 54.7% of pilgrims reported washing their hands more frequently than usual and 89.2% used soap. One hundred and five (36.2%) acquired at least one resistance gene, notably CTX-M A (21.0%), SHV (16.5%) and TEM (8.2%). The strains isolated by culture were mostly E. coli. These bacteria were found to be sensitive to carbapenems and resistant to amoxicillin and amoxicillin-clavulanic acid. The acquisition of enteroaggregative E. coli was independently associated with CTX-M A and TEM acquisition.
Conclusion: Pilgrims presented a risk for acquisition of CTX-M A after the GMT. Surveillance of the prevalence of resistant bacteria and the occurrence of associated clinical infections among pilgrims are necessary in the future.
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| http://dx.doi.org/10.1016/j.tmaid.2024.102709 | DOI Listing |
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Article Synopsis
- - The Grand Magal of Touba (GMT) poses risks of infection for pilgrims, with a study conducted examining the circulation of resistant bacteria among attendees between 2018 and 2021.
- - Out of the pilgrims studied, 31.4% acquired pathogenic bacteria, predominantly Escherichia coli, and 36.2% gained resistance genes, indicating a concerning trend in antibiotic resistance.
- - The findings suggest that pilgrims are at increased risk for acquiring specific resistance genes, particularly CTX-M A, and highlight the need for future surveillance of resistant bacteria and related infections in such gatherings.
Influenza at the 2021 Grand Magal of Touba and possible spread to rural villages in South Senegal - a genomic epidemiological study.
Int J Infect Dis
April 2024
Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France; VITROME, Campus International IRD-UCAD de l'IRD, Dakar, Senegal; IHU-Méditerranée Infection, Marseille, France. Electronic address:
Objectives: Influenza is frequent among pilgrims participating in the Grand Magal de Touba (GMT), in Senegal, with a potential to spread to contacts when they return home.
Methods: Ill pilgrims consulting at a health care center in Mbacké city close to Touba during the 2021 GMT, pilgrims returning to Dielmo and Ndiop villages, and patients who did not travel to Touba and consulted at health care centers in these two villages in 2021 were tested for the influenza virus by polymerase chain reaction on nasopharyngeal samples. Next-generation sequencing and comparative and phylogenetic analyses of influenza A virus genomes were performed.
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