A practical synthetic method for the synthesis of vinyl sulfonyl fluorides through copper-promoted direct fluorosulfonylation has been developed. The reaction of the vinylboronic acids with DABSO and then NFSI is performed under mild reaction conditions. This transformation efficiently affords aryl or alkyl vinyl sulfonyl fluorides with good reaction yields, exclusive -configuration, broad substrate scope, excellent compatibility, and operational simplicity.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.orglett.4c00711 | DOI Listing |
Publication Analysis
Top Keywords
sulfonyl fluorides
12
vinylboronic acids
8
vinyl sulfonyl
8
stereoselective fluorosulfonylation
4
fluorosulfonylation vinylboronic
4
acids -vinyl
4
-vinyl sulfonyl
4
fluorides copper
4
copper participation
4
participation practical
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!