AI Article Synopsis
- The study aimed to evaluate autonomic function differences, specifically heart rate variability (HRV), between individuals with and without orthostatic hypotension (OH), particularly in those with spinal cord injury (SCI).
- Researchers used a tilt table to collect heart rate and blood pressure data in different positions, processing this data to analyze HRV parameters.
- Results indicated that SCI participants with OH showed decreased HRV, particularly in parasympathetic activity, but symptoms of OH were not primarily linked to autonomic function, suggesting other factors might play a significant role.
Article Abstract
Context/objective: To assess differences in autonomic function using heart rate variability (HRV) parameters between people with and without orthostatic hypotension (OH), and to determine symptoms of OH in people with spinal cord injury (SCI).
Methods: R-R interval and blood pressure (BP) data were recorded using Finometer PRO in both the supine position and at a 60-degree tilt using a tilt table, each lasting for 6 minutes. R-R interval data were processed using the Kubios HRV analysis software to convert R-R interval into time and frequency domains for further analysis.
Results: Compared to the non-OH group, the SCI group with OH exhibited lower values for root mean square of the successive differences (RMSSD) and standard deviation of normal-to-normal interval (SDNN), along with an elevated heart rate during tilt-up. Participants with OH symptoms had a lower average heart rate in the supine and 60-degree positions compared to asymptomatic participants. Logistic regression analysis indicated that SDNN in the supine position correlated with the presence of OH, and that the mean heart rate in the 60-degree position was related to the presence of symptoms.
Conclusions: Differences in HRV parameters were observed in people with SCI and OH, suggesting a reduced parasympathetic activity in the supine position, likely as a response to maintain homeostasis in BP regulation. Despite the presence or absence of OH symptoms, there was no difference in HRV parameters. This finding suggests that autonomic function may not be the primary determinant of these symptoms, with other factors likely being more influential.
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| http://dx.doi.org/10.1080/10790268.2024.2326703 | DOI Listing |
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