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Patient Voices: Multimethod Study on the Feasibility of Implementing Electronic Patient-Reported Outcome Measures in a Comprehensive Cancer Center.
JMIR Cancer
January 2025
Scientific Directorate, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milano, Italy.
Background: "Patient Voices" is a software developed to promote the systematic collection of electronic patient-reported outcome measures (ePROMs) in routine oncology clinical practice.
Objective: This study aimed to assess compliance with and feasibility of the Patient Voices ePROM system and analyze patient-related barriers in an Italian comprehensive cancer center.
Methods: Consecutive patients with cancer attending 3 outpatient clinics and 3 inpatient wards were screened for eligibility (adults, native speakers, and being able to fill in the ePROMs) and enrolled in a quantitative and qualitative multimethod study.
Anxiety and Depression Among Patients Newly Diagnosed with Lymphoma and Myeloma.
Blood Adv
January 2025
University of Massachusetts Boston, Boston, Massachusetts, United States.
Although lymphoma and myeloma confer physical and psychological burden, data are limited regarding anxiety and depression symptoms in affected patients. We conducted a survey between 07/2021 and 09/2022 to characterize anxiety and depression in a cohort of adult patients, within six months of a lymphoma or myeloma diagnosis. Clinically significant anxiety and depression symptoms were defined as scores ≥8 on the corresponding subscales of the Hospital Anxiety and Depression Scale.
View Article and Find Full Text PDFSignificance of birth in the maintenance of quiescent neural stem cells.
Sci Adv
January 2025
Department of Developmental and Regenerative Neurobiology, Institute of Brain Science, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi 467-8601, Japan.
Birth is one of the most important life events for animals. However, its significance in the developmental process is not fully understood. Here, we found that birth-induced alteration of glutamine metabolism in radial glia (RG), the embryonic neural stem cells (NSCs), is required for the acquisition of quiescence and long-term maintenance of postnatal NSCs.
View Article and Find Full Text PDFBrazilian version of the OHIP 14 Periodontal Disease Questionnaire: cross cultural adaptation and validation.
Braz Oral Res
January 2025
Universidade Federal dos Vales do Jequitinhonha e Mucuri UFVJM, School of Biological and Health Sciences, Department of Dentistry, Diamantina, MG, Brazil.
Although it is recognized that periodontal disease negatively impacts quality of life, there is no validated instrument to assess this impact in Brazil. This study aimed to translate, cross-culturally adapt, and validate the OHIP 14 PD (Oral Health Impact Profile Applied to Periodontal Diseases) for application among Brazilian patients. The original instrument was translated and validated into Brazilian Portuguese in a cross-sectional study with 110 participants recruited from a Dental School clinic.
View Article and Find Full Text PDFPractitioner, patient and public views on the acceptability of mobile stroke units in England and Wales: A mixed methods study.
PLoS One
January 2025
Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, United Kingdom.
Background: Evidence for Mobile Stroke Units (MSUs) demonstrates that onset to treatment times for intravenous thrombolysis can be reduced and access to mechanical thrombectomy might be improved. Despite growing use of MSUs internationally, to date there have been no studies in NHS England and NHS Wales exploring the acceptability of MSUs to clinicians, patient and public representatives and other key stakeholders, which are important when considering potential feasibility and implementation.
Methods: This study used a mixed methods design with a cross-sectional survey and qualitative workshops and interviews between October 2023 to May 2024.
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