Introduction: Despite the ecological nature of episodic memory (EM) and the importance of consolidation in its functioning, studies tackling both subjects are still scarce. Therefore, the present study aims at establishing predictions of the future of newly encoded information in EM in an ecological paradigm.
Methods: Participants recorded two personal events per day with a SenseCam portable camera, for 10 days, and characterized the events with different subjective scales (emotional valence and intensity, self-concept and self-relevance, perspective and anticipated details at a month, mental images…). They then performed a surprise free recall at 5 days and 1 month after encoding. Machine learning algorithms were used to predict the future of events (episodic or forgotten) in memory at 1 month.
Results: The best algorithm showed an accuracy of 78%, suggesting that such a prediction is reliably possible. Variables that best differentiated between episodic and forgotten memories at 1 month were mental imagery, self-reference, and prospection (anticipated details) at encoding and the first free recall.
Discussion: These results may establish the basis for the development of episodic autobiographical memory during daily experiences.
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http://dx.doi.org/10.3389/fpsyg.2024.1355343 | DOI Listing |
J Chem Theory Comput
December 2024
Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 3, 9747 AG Groningen, The Netherlands.
We present the implementation of the time-domain multichromophoric fluorescence resonant energy transfer (TC-MCFRET) approach in the numerical integration of the Schrödinger equation (NISE) program. This method enables the efficient simulation of incoherent energy transfer between distinct segments within large and complex molecular systems, such as photosynthetic complexes. Our approach incorporates a segmentation protocol to divide these systems into manageable components and a modified thermal correction to ensure detailed balance.
View Article and Find Full Text PDFJ Med Internet Res
December 2024
Else Kröner Fresenius Center for Digital Health, Dresden University of Technology, Dresden, Germany.
Background: The integration of connected medical devices (MDs) into health care brings benefits but also introduces new, often challenging-to-assess risks related to cybersecurity, which have the potential to harm patients. Current regulations in the European Union and the United States mandate the consideration of these risks in the benefit-risk analysis (BRA) required for MD approval. This important step in the approval process weighs all the defined benefits of a device with its anticipated risks to ensure that the product provides a positive argument for use.
View Article and Find Full Text PDFCommun Biol
December 2024
Department of Instrumentation and Applied Physics, Indian Institute of Science, Bangalore, 560012, India.
Single-molecule localization microscopy (SMLM) can decipher fine details that are otherwise impossible using diffraction-limited microscopy. Often, the reconstructed super-resolved images suffer from noise, strong background and are prone to false detections that may impact quantitative imaging. To overcome these limitations, we propose a technique (corrSMLM) that recognizes and detects fortunate molecules (molecules with long blinking cycles) from the recorded data.
View Article and Find Full Text PDFJAMA Cardiol
December 2024
The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, New York.
Importance: Drug-coated balloon (DCB) angioplasty has emerged as an alternative to drug-eluting stent (DES) implantation for percutaneous coronary intervention (PCI) in patients with coronary in-stent restenosis (ISR) as well as de novo coronary artery disease.
Observations: DCBs are balloons coated with antiproliferative agents and excipients, whose aim is to foster favorable vessel healing after appropriate lesion preparation. By providing homogeneous antiproliferative drug delivery in the absence of permanent foreign body implantation, DCBs offer multiple advantages over DES, including preservation of vessel anatomy and function and positive vessel remodeling.
BMC Complement Med Ther
December 2024
College of Medicine, University of Florida, Gainesville, FL, USA.
Background: As the primary cause of various preventable illnesses, smoking results in approximately five million premature deaths each year in the US and a multitude of adults living with serious illness. The majority of smokers know the health risks associated with smoking and intend to quit. However, quitting is very difficult partly because of insomnia and stress associated with it.
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