Memory and learning are essential cognitive processes that enable us to obtain, retain, and recall information [...].
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10931689 | PMC |
http://dx.doi.org/10.3390/ijms25052724 | DOI Listing |
BMC Pharmacol Toxicol
January 2025
Yanzhou District People's Hospital, Jining, Shandong, China.
Background: Osteoporosis (OP), often termed the "silent epidemic," poses a substantial public health burden. Emerging insights into the molecular functions of FBXW4 have spurred interest in its potential roles across various diseases.
Methods: This study explored FBXW4 by integrating DEGs from GEO datasets GSE2208, GSE7158, GSE56815, and GSE35956 with immune-related gene compilations from the ImmPort repository.
Mol Neurodegener
January 2025
The Picower Institute for Learning and Memory, Cambridge, MA, USA.
Many diseases and disorders of the nervous system suffer from a lack of adequate therapeutics to halt or slow disease progression, and to this day, no cure exists for any of the fatal neurodegenerative diseases. In part this is due to the incredible diversity of cell types that comprise the brain, knowledge gaps in understanding basic mechanisms of disease, as well as a lack of reliable strategies for delivering new therapeutic modalities to affected areas. With the advent of single cell genomics, it is now possible to interrogate the molecular characteristics of diverse cell populations and their alterations in diseased states.
View Article and Find Full Text PDFSci Rep
January 2025
School of Architecture and Urban Planning, Beijing University of Civil Engineering and Architecture, Beijing, 100055, China.
Air pollution is a critical global environmental issue, further exacerbated by rapid industrialization and urbanization. Accurate prediction of air pollutant concentrations is essential for effective pollution prevention and control measures. The complex nature of pollutant data is influenced by fluctuating meteorological conditions, diverse pollution sources, and propagation processes, underscores the crucial importance of the spatial and temporal feature extraction for accurately predicting air pollutant concentrations.
View Article and Find Full Text PDFSci Rep
January 2025
Department of MRI, Shaanxi Provincial People's Hospital, Xi'an, China.
Early detection of cognitive dysfunction in patients with type 2 diabetes mellitus (T2DM) is important for preventive measures due to the lack of effective treatments. The purpose of this study is to investigate the relationship between enlarged perivascular space in the hippocampus (H-EPVS) and cognitive performance in patients with T2DM, and to determine whether it can serve as an imaging marker for cognitive dysfunction. 66 T2DM patients with cognitive impairment (T2DM-CI) and 71 T2DM patients with normal cognitive function (T2DM-NC) underwent cranial MRI scans and comprehensive neuropsychological assessments.
View Article and Find Full Text PDFSci Rep
January 2025
Faculty of Science and Technology, Suan Sunandha Rajabhat University, Bangkok, 10300, Thailand.
Attention mechanisms such as the Convolutional Block Attention Module (CBAM) can help emphasize and refine the most relevant feature maps such as color, texture, spots, and wrinkle variations for the avocado ripeness classification. However, the CBAM lacks global context awareness, which may prevent it from capturing long-range dependencies or global patterns such as relationships between distant regions in the image. Further, more complex neural networks can improve model performance but at the cost of increasing the number of layers and train parameters, which may not be suitable for resource constrained devices.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!