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Exposure to an enriched environment and fucoidan supplementation ameliorate learning and memory function in rats subjected to global cerebral ischemia.
Neurosci Lett
December 2024
Department of Anatomy, Dr. Arcot Lakshmanasamy Mudaliar Post Graduate Institute of Basic Medical Sciences, University of Madras, Chennai, India. Electronic address:
An enriched environment (EE) constitutes a proficient strategy that instigates social, cognitive, and motor faculties, fostering healing and heightening learning and memory function after ischemia, while fucoidan derived from brown seaweed encompasses a diverse array of bioactivities and is known to possess neuroprotective properties. This study aims to investigate the effectiveness of combining fucoidan and EE in a rat model of vascular dementia to overcome cognitive challenges. The rats were randomly assigned as Sham, Lesion - 4-vessel occlusion (4VO) i.
View Article and Find Full Text PDFEffects of brown seaweed oligosaccharides on obesity and constipation managements.
J Food Sci
December 2024
College of Food Science and Nutritional Engineering, China Agricultural University, Beijing, China.
Brown seaweed oligosaccharides (BSO) have demonstrated potential as nutraceuticals with cholesterol-lowering, anti-obesity, and anti-constipation properties. In this study, we initially examined how BSO impact body weight, blood lipid levels, and adipose tissue in a rat model of obesity induced by a high-fat diet. Our findings revealed that BSO administration significantly attenuated body weight gain, ameliorated dyslipidemia, and reduced visceral adiposity.
View Article and Find Full Text PDFDecellularized Green and Brown Macroalgae as Cellulose Matrices for Tissue Engineering.
J Funct Biomater
December 2024
Department of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin 9054, New Zealand.
Scaffolds resembling the extracellular matrix (ECM) provide structural support for cells in the engineering of tissue constructs. Various material sources and fabrication techniques have been employed in scaffold production. Cellulose-based matrices are of interest due to their abundant supply, hydrophilicity, mechanical strength, and biological inertness.
View Article and Find Full Text PDFThe Beneficial Roles of Seaweed in Atopic Dermatitis.
Mar Drugs
December 2024
Department of Smart Green Technology Engineering, Pukyong National University, Busan 48513, Republic of Korea.
Atopic dermatitis (AD) is a chronic, inflammatory skin condition characterized by severe pruritus and recurrent flare-ups, significantly impacting patients' quality of life. Current treatments, such as corticosteroids and immunomodulators, often provide symptomatic relief but can lead to adverse effects with prolonged use. Seaweed, a sustainable and nutrient-dense resource, has emerged as a promising alternative due to its rich bioactive compounds-polysaccharides, phlorotannins, polyphenols, and chlorophyll-that offer anti-inflammatory, antioxidant, and immunomodulatory properties.
View Article and Find Full Text PDFAbiotic Factors Modulating Metabolite Composition in Brown Algae (Phaeophyceae): Ecological Impacts and Opportunities for Bioprospecting of Bioactive Compounds.
Mar Drugs
December 2024
Laboratory of Natural Products from Seaweeds (ALGAMAR), Department of Marine Biology, Institute of Biology, Federal Fluminense University, Niterói 24210-201, RJ, Brazil.
Brown algae are vital structural elements and contributors to biodiversity in marine ecosystems. These organisms adapt to various environmental challenges by producing primary and secondary metabolites crucial for their survival, defense, and resilience. Besides their ecological role, these diverse metabolites have potential for biotechnological applications in industries including pharmaceuticals, cosmetics, and food.
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