State of the kallikrein-kinin system components (activity of kallikrein and total esterase activity of trypsin-like enzymes) was studied in synovial fluid at the acute period of the knee joint closed injury. The kallikrein activity as well as the esterase activity of trypsin-like enzymes correlated completely with clinical manifestations of the reactive arthritis. These enzymes appear to have a definite importance in development of inflammation in the joint.

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