AI Article Synopsis
- - A 29-year-old woman with a high fever underwent surgery for a suspected gallbladder or liver issue, but a solid tumor in her adrenal gland was discovered instead.
- - The tumor's frozen section did not provide a definitive diagnosis, leading to further histological examination which revealed large histiocyte-like cells with specific markers.
- - The final diagnosis was xanthogranulomatous adrenalitis, and potential other conditions like Langerhans cell histiocytosis and Rosai-Dorfman disease were considered in the differential diagnosis.
Article Abstract
A radiologically diagnosed tumor in a 29-year-old woman with a fever of around 39 °C was operated on under the suspicion of cholecystitis or a liver abscess. A solid tumor was found in the adrenal gland and resected. The frozen section findings did not reveal a clear diagnosis of entity and assignment. Histologically, the tumor was found to consist of densely clustered large histiocyte-like cells with expression of vimentin, CD68, and CD163 as well as negativity for keratin, langerin, and SMA. We diagnosed xanthogranulomatous adrenalitis and discussed the differential diagnoses (Langerhans cell histiocytosis, Rosai-Dorfman disease, malakoplakia, Erdheim-Chester disease).
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11045564 | PMC |
| http://dx.doi.org/10.1007/s00292-024-01312-x | DOI Listing |
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