The impact-intensive and rapidly growing pharmaceutical industry must ensure its sustainability. This study reveals that environmental sustainability assessments have been conducted for only around 0.2% of pharmaceuticals, environmental impacts have significant variations among the assessed products, and different impact categories have not been consistently studied. Highly varied impacts require assessing more products to understand the industry's sustainability status. Reporting all impact categories will be crucial, especially when comparing production technologies. Biological production of (semi)synthetic pharmaceuticals could reduce their environmental costs, though the high impacts of biologically produced monoclonal antibodies should also be optimized. Considering the sustainability potential of biopharmaceuticals from economic, environmental, and social perspectives, collaboratively guiding their immense market growth would lead to the industry's sustainability transition.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.copbio.2024.103100 | DOI Listing |
BMC Health Serv Res
January 2025
Department of Biological Sciences, Faculty of Science, Kyambogo University, Kampala, Uganda.
Background: A key concern for global public health is nosocomial infections. Essential to the fight against nosocomial infection, is healthcare professionals' knowledge and attitudes. Therefore, this study investigated healthcare professionals' knowledge and attitudes toward nosocomial infection at the Kiruddu Referral Hospital, Kampala, Uganda.
View Article and Find Full Text PDFBMC Oral Health
January 2025
Bangkok Hospital Dental Center Holistic Care and Dental Implant, Bangkok Hospital, Bangkok, 10310, Thailand.
Background: Assessing the difficulty of impacted lower third molar (ILTM) surgical extraction is crucial for predicting postoperative complications and estimating procedure duration. The aim of this study was to evaluate the effectiveness of a convolutional neural network (CNN) in determining the angulation, position, classification and difficulty index (DI) of ILTM. Additionally, we compared these parameters and the time required for interpretation among deep learning (DL) models, sixth-year dental students (DSs), and general dental practitioners (GPs) with and without CNN assistance.
View Article and Find Full Text PDFTher Innov Regul Sci
January 2025
Bayer AG, Pharmaceuticals R&D, Bayer AG, Muellerstr. 178, 13342, Berlin, Germany.
Medicine is increasingly supported by software, with digital health technologies offering innovative ways to capture insights and drive therapies. Globally, medical device software must follow regulatory processes based on risk classification. The introduction of MDR represents a significant shift in risk-based classification for Medical Devices in Europe, including classification Rule 11 for software, which has caused significant discussions among European regulators.
View Article and Find Full Text PDFComput Biol Med
January 2025
Khalifa University, Abu Dhabi, United Arab Emirates. Electronic address:
Musculoskeletal modeling based on inverse dynamics provides a cost-effective non-invasive means for calculating intersegmental joint reaction forces and moments, solely relying on kinematic data, easily obtained from smart wearables. On the other hand, the accuracy and precision of such models strongly hinge upon the selected scaling methodology tailored to subject-specific data. This study investigates the impact of upper body mass distribution on internal and external kinetics computed using a comprehensive musculoskeletal model during level walking in both normal weight and obese individuals.
View Article and Find Full Text PDFEur J Oncol Nurs
January 2025
Faculty of Psychology and Education Sciences, Centre for Social Studies (CES), University of Coimbra, USA.
Purpose: Long-term caregiving tasks can be exhausting for family caregivers, resulting in high psychological morbidity. The study aims to explore the experiences, challenges, and strengths of family caregivers providing care for cancer patients in palliative care, in-patient or at home.
Method: Nine caregivers were included, predominantly women aged 34 to 70, from various regions of Portugal.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!