AI Article Synopsis
- A phytochemical study of the green walnut husks from Maxim. led to the discovery of three new triterpenoids, named juglansmanoids A-C.
- The structures of these compounds were determined using advanced techniques like NMR spectroscopy and mass spectrometry.
- The triterpenoids showed strong anti-hyaluronidase activity, being three times more effective than the control drug oleanolic acid.
Article Abstract
Phytochemical study on 90% ethanol extract from the green walnut husks of Maxim. resulted into the isolation of three undescribed triterpenoids, juglansmanoids A-C (-). Structural elucidation of all the compounds were performed by spectral methods such as 1D and 2D (H-H COSY, HMQC, and HMBC) NMR spectroscopy, in addition to high resolution mass spectrometry. The isolated components were evaluated for anti-hyaluronidase activities. As a result, triterpenoid exhibited potent anti-hyaluronidase activity (IC = 9.78 μg/ml) three times more than the positive control drug oleanolic acid (IC = 40.12 μg/ml).
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| http://dx.doi.org/10.1080/10286020.2024.2327514 | DOI Listing |
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