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Clinical Image: Extensive subcutaneous calcinosis cutis with fistulization in refractory dermatomyositis.
ACR Open Rheumatol
January 2025
Madonna del Popolo Hospital, Omegna, Italy.
Native Valve and Native Neo-Sinus Remodeling Following Transcatheter Aortic Valve Replacement.
Circ Cardiovasc Interv
December 2024
Cardiovascular Translational Laboratory, Providence Research and Centre for Heart Lung Innovation, Vancouver, British Columbia, Canada (J.Y., H.G., J.J., A.L., J.G.W., J.S., D.M., S.L.S.).
Background: Transcatheter aortic valve replacement (TAVR) pushes aside the diseased native aortic valve and creates a native neo-sinus bordered by the aortic root wall and the displaced native valve. There are limited data on the progression of native valve disease post-TAVR and no previous analysis of the native neo-sinus.
Methods: Native aortic valves and native neo-sinus explants obtained post-TAVR were evaluated histologically (hematoxylin and eosin, Movat pentachrome, and Martius Scarlet Blue stains) and by immunohistochemistry (TGF-β1 [transforming growth factor-beta 1], FAP [fibroblast activation protein], and ALP [alkaline phosphatase]) to assess disease mechanisms.
Prognostic importance of extensive coronary calcium on lung cancer screening chest computed tomography.
CMAJ
December 2024
Medicine Division of Cardiology, (Cabral Caires, Mbondo Kasuku, Mengesha, Paterson, Chen, Chow, Small), University of Ottawa Heart Institute; Department of Cardiology (Garuba, Law, Johnson), The Ottawa Hospital; Department of Radiology (Dennie, Pena), University of Ottawa, Ottawa, Ont.
Article Synopsis
- Low-dose chest CT, commonly used for lung cancer screening, also detects coronary artery disease by identifying coronary artery calcium.
- In a study of 1486 high-risk lung cancer patients, 82.9% had coronary artery calcium, with 29.5% showing extensive levels.
- Extensive coronary artery calcium significantly predicted higher risks of all-cause death and cardiovascular events, highlighting the potential benefits of lung cancer screenings for detecting heart health issues.
Intravascular lithotripsy in infra-popliteal peripheral artery disease.
J Cardiovasc Surg (Torino)
October 2024
Department of Vascular Surgery, Prince of Wales Hospital, Sydney, Australia -
Chronic limb-threatening ischemia (CLTI) carries a significant risk of limb loss and thus demands urgent attention. Calcified atherosclerotic disease affecting the infra-popliteal (IP) arteries poses a formidable challenge for effective revascularization due to the narrow vessel diameter and the common presence of extensively calcified, long occlusive lesions. Intravascular lithotripsy (IVL) is an endovascular treatment that induces microfractures in the medial calcifications of blood vessels, thereby facilitating the clearance of calcified obstructive arterial lesions.
View Article and Find Full Text PDF[The modified hugging balloon technique].
G Ital Cardiol (Rome)
November 2024
S.C. Cardiologia, Ospedale S.G. Bosco, ASL Città di Torino, Torino.
Article Synopsis
- Percutaneous coronary intervention (PCI) has greatly improved treatments for coronary artery disease, but in-stent restenosis (ISR) remains a significant issue, especially when complicated by calcification.
- Various techniques exist for treating calcified ISR, including super-high-pressure balloon dilation, atherectomy methods, and intravascular lithotripsy (IVL).
- This case report discusses a patient with severe, calcified ISR in a large artery, showcasing the use of shockwave lithotripsy combined with balloon dilation to improve stent expansion, highlighting the effectiveness of innovative approaches for difficult ISR cases.
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