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http://dx.doi.org/10.3389/fpubh.2024.1353982 | DOI Listing |
Science
January 2025
Gastroenterology Division, Massachusetts General Hospital, Boston, MA, USA.
Bile acids differentially affect immune cell responses to liver cancer.
View Article and Find Full Text PDFFront Psychiatry
December 2024
Research Center for Child Mental Development, Hamamatsu University School of Medicine, Hamamatsu, Japan.
PLoS Biol
January 2025
Research Group Meiotic Recombination and Genome Instability, Max Planck Institute for Evolutionary Biology, Plön, Germany.
A recent study in PLOS Biology on the epigenetic recombination regulator PRDM9 in salmonid fish reveals that its function has been preserved across vertebrates for hundreds of millions of years, with rapidly evolving DNA-binding domains being a defining attribute.
View Article and Find Full Text PDFThe European Commission's Strategy for the Rights of Persons with Disabilities 2021-2030 aims to ensure equal opportunities and rights for all individuals, including those with intellectual disabilities. People with intellectual disabilities are often underrepresented in cancer prevention and screening policies, leading to disparities in health outcomes and early mortality. The intersection of intellectual disability, cancer, and depression represents an underexplored area in healthcare research.
View Article and Find Full Text PDFAm J Epidemiol
January 2025
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.
We recently questioned the utility of testing for proportional hazards in survival analysis. Here we expand on why the proportional hazards assumption is both implausible and unnecessary in most medical studies, particularly in randomized trials. We conclude that using survival analysis methods that do not rely on proportional hazards is typically the preferred course of action.
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