AI Article Synopsis
- Large-scale imaging of neuronal activities is essential for understanding brain functions, but real-time data analysis has been a challenge.
- The development of a real-time analysis system using a field programmable gate array and graphics processing unit allows for processing image streams of up to 500 megabytes per second.
- This system is specifically adapted for whole-brain imaging of awake larval zebrafish and can extract activity from 100,000 neurons, facilitating closed-loop investigations of neural dynamics.
Article Abstract
Large-scale imaging of neuronal activities is crucial for understanding brain functions. However, it is challenging to analyze large-scale imaging data in real time, preventing closed-loop investigation of neural circuitry. Here we develop a real-time analysis system with a field programmable gate array-graphics processing unit design for an up to 500-megabyte-per-second image stream. Adapted to whole-brain imaging of awake larval zebrafish, the system timely extracts activity from up to 100,000 neurons and enables closed-loop perturbations of neural dynamics.
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| http://dx.doi.org/10.1038/s41593-024-01595-6 | DOI Listing |
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