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| http://dx.doi.org/10.21142/2523-2754-0902-2021-053 | DOI Listing |
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Regulation of INPP5E in Ciliogenesis, Development, and Disease.
Int J Biol Sci
January 2025
Department of Basic & Translational Sciences, School of Dental Medicine, University of Pennsylvania, USA.
Inositol polyphosphate-5-phosphatase E (INPP5E) is a 5-phosphatase critically involved in diverse physiological processes, including embryonic development, neurological function, immune regulation, hemopoietic cell dynamics, and macrophage proliferation, differentiation, and phagocytosis. Mutations in cause Joubert and Meckel-Gruber syndromes in humans; these are characterized by brain malformations, microphthalmia, situs inversus, skeletal abnormalities, and polydactyly. Recent studies have demonstrated the key role of INPP5E in governing intracellular processes like endocytosis, exocytosis, vesicular trafficking, and membrane dynamics.
View Article and Find Full Text PDFOral Myiasis in a 6-year-old Child with Cerebral Palsy: A Case Report.
Int J Clin Pediatr Dent
November 2024
Department of Pedodontics and Preventive Dentistry, Government Dental College and Hospital, Hyderabad, Telangana, India.
Aims And Background: Myiasis is an infestation of live humans or animals with dipterous larvae that feed on the host's live or dead tissue. The incidence of oral myiasis is rare and even less common in children. Poor oral hygiene, neurological disabilities, bedridden or locomotor disabilities, low socioeconomic status, malnutrition, etc.
View Article and Find Full Text PDFIncidence of postoperative pain after single-visit and multiple-visit root canal therapy: a systematic review.
BMC Oral Health
January 2025
Department of Conservative Dentistry and Endodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, 600077, Tamil Nadu, India.
AIM- The objective of the systematic review is to evaluate the incidence of postoperative pain after single-visit and multiple-visit root canal therapy. METHODS- Published research indexed in PubMed or Scopus or Cochrane or DOAJ or Web of Science evaluating the frequency percentage of postoperative aching after one and several root canal therapy appointments through randomized controlled trials or prospectively were included. RESULT- Most surveys utilized VAS (Visual Analogue Scale) to estimate the degree of pain among the participants.
View Article and Find Full Text PDFFeasibility of occlusal plane in predicting the changes in anteroposterior mandibular position: a comprehensive analysis using deep learning-based three-dimensional models.
BMC Oral Health
January 2025
Department of Stomatology, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Foshan, 528308, Guangdong, China.
Background: A comprehensive analysis of the occlusal plane (OP) inclination in predicting anteroposterior mandibular position (APMP) changes is still lacking. This study aimed to analyse the relationships between inclinations of different OPs and APMP metrics and explore the feasibility of OP inclination in predicting changes in APMP.
Methods: Overall, 115 three-dimensional (3D) models were reconstructed using deep learning-based cone-beam computed tomography (CBCT) segmentation, and their accuracy in supporting cusps was compared with that of intraoral scanning models.
Synthesis, characterization, and evaluation of copper-doped zinc oxide nanoparticles anticancer effects: in vitro and in vivo experiments.
BMC Cancer
January 2025
Finetech in Medicine Research Center, Iran University of Medical Sciences, Tehran, Iran.
Background And Aim: Zinc oxide and copper oxide nanoparticles are known for their promising biological activities. This study aims to synthesize zinc oxide nanoparticles and copper-doped zinc oxide nanoparticles to harness the combined cytotoxic and anticancer effects of them in vitro and in vivo studies.
Methods: Zinc oxide nanoparticles, both doped and undoped, were synthesized using a chemical co-precipitation method.
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