AI Article Synopsis

  • * A key sign of this disease is the presence of Kayser-Fleischer rings, which are deposits of copper around the cornea of the eye.
  • * These rings are crucial for diagnosing Wilson's disease and highlight the disease's relationship with copper buildup in the body.

Article Abstract

Wilson's disease is a genetic disorder of copper metabolism that primarily manifests with hepatic and neurological features. Kayser-Fleischer rings (KF rings) are pathognomonic of Wilson's disease and helps in establishing its diagnosis.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10920319PMC
http://dx.doi.org/10.1002/ccr3.8642DOI Listing

Publication Analysis

Top Keywords

wilson's disease
12
kayser-fleischer rings
8
rings pathognomonic
8
pathognomonic wilson's
8
disease wilson's
4
disease genetic
4
genetic disorder
4
disorder copper
4
copper metabolism
4
metabolism manifests
4

Similar Publications

An 11-year-old girl with quiescent ulcerative colitis had sustained elevation of liver enzymes. Although she had no clinical symptoms suggestive of Wilson's disease, such as Kayser-Fleischer rings, laboratory data showed decreased serum copper and ceruloplasmin levels and increased urinary copper excretion. Genetic testing showed pathogenic variants in allele 1: c.

View Article and Find Full Text PDF

Biomarkers.

Alzheimers Dement

December 2024

Newcastle University, Newcastle Upon Tyne, UK.

Background: Outdoor air pollution is a global issue which poses a significant health risk. Modern neuroimaging techniques have revealed the detrimental impact of air pollution on brain health, in particular the development and progression of neurodegenerative diseases such as Alzheimer's disease (AD). We conducted a systematic review to evaluate the effects of long-term (months to years) exposure to outdoor air pollutants on the development and progression of AD using neuroimaging data.

View Article and Find Full Text PDF

Biomarkers.

Alzheimers Dement

December 2024

Newcastle University, Newcastle Upon Tyne, UK.

Background: Using digital technologies to detect the early signs of dementia-causing diseases could improve the timely detection of these diseases. To support this approach, we explored users' perspectives on the acceptability of using a variety of digital technologies.

Method: A sub-group of participants from Boston University's Alzheimer's Disease Research Centre were recruited.

View Article and Find Full Text PDF

Background: Using digital technologies to detect the early signs of dementia-causing diseases could improve the timely detection of these diseases. To support this approach, we explored users' perspectives on the acceptability of using a variety of digital technologies.

Method: A sub-group of participants from Boston University's Alzheimer's Disease Research Centre were recruited.

View Article and Find Full Text PDF

When systematic lupus erythematosus-like lab results (e.g., positive anti-double-stranded DNA antibody, low complement component 3) are inconsistent with physical findings, such as the absence of arthritis or nephritis, clinicians should consider diagnoses such as Wilson's disease, especially in the presence of abnormal liver function and elevated international normalized ratio (INR).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!