Internal limiting membrane (ILM) peeling is a critical step in the process of macular hole surgery, giving rise to various modified techniques such as ILM flip-over coverage, ILM and other tissue tamponade procedures, and foveal-sparing ILM peeling. All these approaches aim to improve the postoperative closure rate of macular holes. The goal of macular hole surgery is to better preserve the integrity of the foveal center structure, with the aim of achieving functional recovery on the basis of anatomical restoration. However, in clinical practice, there is a tendency to excessively choose certain surgical methods solely to pursue the closure rate of the hole, which may not be beneficial for the visual function recovery of the patients. This article discusses how to correctly select the internal limiting membrane and its derivative procedures in macular hole surgery, combining clinical practice and relevant domestic and international research literature. It aims to provide insights for colleagues performing macular hole surgery as a reference regarding this clinical focus issue.
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http://dx.doi.org/10.3760/cma.j.cn112142-20231225-00307 | DOI Listing |
Ophthalmol Retina
March 2025
Eye Clinic, Department of Biomedical and Clinical Science "Luigi Sacco," Sacco Hospital, University of Milan, Italy.
Retina
March 2025
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.
Purpose: This study introduces the Cloverleaf Internal Limiting Membrane (ILM) flap technique for managing challenging macular holes, aiming to enhance ILM flap placement and improve functional and anatomical outcomes.
Methods: A retrospective review of cases undergoing the Cloverleaf ILM flap technique was conducted at a single center. This technique involves creating multiple ILM flaps in a cloverleaf configuration in order to enhance the stability and coverage of the macular hole.
Retina
March 2025
University of Ferrara, Department of Translational Medicine, Ferrara, Italy.
Purpose: To report the visual and anatomical outcomes of Descemet membrane epiretinal graft for refractory full-thickness macular holes (MH).
Methods: This interventional case series included patients with refractory MH who previously underwent standard pars plana vitrectomy with internal limiting membrane peeling for repair of MH with no success. Donor corneas unsuitable for keratoplasty were stripped at the Eye Bank.
Retina
March 2025
Department of Ophthalmology, Inselspital, University Hospital of Bern, Bern Switzerland.
Purpose: To determine the incidence, prognostic factors and management of macular edema (ME) associated with silicone oil (SO) tamponade.
Methods: This retrospective, comparative, observational study included patients who underwent pars plana vitrectomy (PPV) and SO tamponade for rhegmatogenous retinal detachment (RRD) or persistent full-thickness macular hole (FTMH). Demographic data, clinical characteristics, and OCT findings were analyzed, focusing on the presence of ME.
Cureus
February 2025
Department of Ophthalmology, Salmaniya Medical Complex, Manama, BHR.
Inherited macular dystrophies are a heterogeneous group of disorders characterized by loss of central vision due to macular and retinal pigment epithelium atrophy. Mutations include ABCA4 and BEST1 genes, which are found in different conditions such as Stargardt disease, Best disease, and also in age-related maculopathies. We report a case of retinal detachment and macular hole (MH) in a middle-aged patient with both ABCA4 and BEST1 mutations.
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