AI Article Synopsis

  • A study examined the link between autoimmune inner ear disease and patients with polymyositis (PM) or dermatomyositis (DM) using Taiwan's National Health Insurance Research Database.
  • The research included 1622 PM/DM patients compared to 8109 matched patients without PM/DM, focusing on inner ear symptoms like tinnitus, hearing loss, and vertigo.
  • Results showed that PM/DM patients experienced higher rates of tinnitus (16.1% vs. 12.7%), non-conductive hearing loss (9.2% vs. 6.8%), and vertigo (14.4% vs. 11.1%), indicating a significant association between PM/DM and these symptoms.

Article Abstract

Little is known about a possible association of autoimmune inner ear disease among patients diagnosed with polymyositis (PM)/dermatomyositis (DM). This study aimed to explore differences in the prevalence of inner ear symptoms among patients with and without PM/DM using a nationwide population-based dataset. Data for this study were retrieved from the Taiwan National Health Insurance Research Database. The study sample included 1622 patients diagnosed with PM/DM and 8109 propensity-score matched comparison patients without PM/DM. We performed multivariate logistic regressions to calculate odds ratios (ORs) and 95% confidence interval (CI) for tinnitus, hearing loss, sudden deafness, and vertigo among patients with PM/DM versus comparison patients. Chi-square tests showed statistically significant differences between patients with PM/DM and comparison patients in the prevalence of tinnitus (16.1% vs. 12.7%, p < 0.001), non-conductive hearing loss (9.2% vs. 6.8%, p < 0.001), and vertigo (14.4% vs. 11.1%, p < 0.001). The adjusted ORs for tinnitus, non-conductive hearing loss, and vertigo, respectively, were 1.332 (95% CI = 1.147-1.547), 1.399 (95% CI = 1.154-1.696), and 1.374 (95% CI = 1.173-1.611) for patients with PM/DM when compared to comparison patients. Our study finds that patients with PM/DM have higher prevalence rates of tinnitus, non-conductive hearing loss, and vertigo than comparison patients.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10923884PMC
http://dx.doi.org/10.1038/s41598-024-56372-zDOI Listing

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