The management of young patients with cancer presents several unique challenges. In general, these patients are ill prepared for the diagnosis and the impact on their fertility. With the improved survival for all tumour types and stages, the need for adequate fertility counselling and a multidisciplinary approach in the reproductive care of these patients is paramount. Recent advances in cryopreservation techniques allow for the banking of spermatozoa, oocytes, embryos and ovarian tissue without compromising survival. This Canadian Fertility and Andrology Society (CFAS) guideline outlines the current understanding of social and medical issues associated with oncofertility, and the medical and surgical technologies available to optimize future fertility.
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http://dx.doi.org/10.1016/j.rbmo.2023.103767 | DOI Listing |
Curr Oncol
November 2024
Department of Oncology, Division of Psychosocial Oncology, University of Calgary, Calgary, AB T2S 3C3, Canada.
Survivors of childhood cancer face reduced fertility, which can be a significant cause for concern. Our study aimed to assess the prevalence of fertility-related concerns and identify associated factors. Self-report data were collected with the Long-Term Survivor Questionnaire at the Alberta Children's Hospital's Long-Term Survivor Clinic (LTSC) between January 2021 and September 2023.
View Article and Find Full Text PDFToxicology
December 2024
Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Canada; School of Environmental Studies, Queen's University, Kingston, Canada. Electronic address:
Bisphenol A (BPA) is an organic synthetic chemical used worldwide. Billions of pounds of BPA are produced annually through industrial processes to be used in commercial products, making human exposure to BPA ubiquitous. Concerns have been raised due to the potential adverse health effects of BPA, specifically in vulnerable populations, such as pregnant persons and children.
View Article and Find Full Text PDFHum Reprod
December 2024
Department of Health and Society, University of Toronto Scarborough, Toronto, ON, Canada.
Study Question: What is the association between infertility with or without fertility treatment and incident onset of systemic autoimmune rheumatic disease (SARD) among women who give birth?
Summary Answer: Women who experienced infertility but did not use fertility treatment had a higher incidence of SARD up to 9 years after delivery than those who did not experience infertility, even after accounting for their higher rates of preeclampsia, spontaneous preterm birth, and stillbirth.
What Is Known Already: Infertility is increasingly common and is an under-appreciated risk marker for chronic diseases in women. Despite several studies documenting abnormal immune activity in women with infertility, little is known about the association between infertility and incidence of autoimmune diseases such as SARD which disproportionately develops in reproductive-aged women.
BJOG
November 2024
Tommy's National Centre for Miscarriage Research, Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, UK.
Objective: To examine the association between periconceptual maternal diet and miscarriage risk among women with recurrent miscarriages.
Design: Prospective multicentre cohort study (Tommy's Net).
Setting: Three university hospital research centres in the United Kingdom.
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