Hopfield attractor networks are robust distributed models of human memory, but they lack a general mechanism for effecting state-dependent attractor transitions in response to input. We propose construction rules such that an attractor network may implement an arbitrary finite state machine (FSM), where states and stimuli are represented by high-dimensional random vectors and all state transitions are enacted by the attractor network's dynamics. Numerical simulations show the capacity of the model, in terms of the maximum size of implementable FSM, to be linear in the size of the attractor network for dense bipolar state vectors and approximately quadratic for sparse binary state vectors. We show that the model is robust to imprecise and noisy weights, and so a prime candidate for implementation with high-density but unreliable devices. By endowing attractor networks with the ability to emulate arbitrary FSMs, we propose a plausible path by which FSMs could exist as a distributed computational primitive in biological neural networks.
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http://dx.doi.org/10.1162/neco_a_01638 | DOI Listing |
Eur J Dent
March 2025
Department of Dental Materials Science, Academic Centre for Dentistry Amsterdam (ACTA), Universiteit van Amsterdam and Vrije Universiteit, Amsterdam, North Holland, the Netherlands.
Objectives: This article evaluates the marginal and internal gap, interfacial volume, and fatigue behavior in computer-aided design-computer-aided manufacturing (CAD-CAM) restorations with different designs (crowns or endocrowns) made from lithium disilicate-based ceramic (LD, IPS e.max CAD, Ivoclar AG) or resin composite (RC, Tetric CAD, Ivoclar AG).
Materials And Methods: Simplified LD and RC crowns (-C) and endocrowns (-E) were produced ( = 10) using CAD-CAM technology, through scanning (CEREC Primescan, Dentsply Sirona) and milling (CEREC MC XL, Dentsply Sirona), and then adhesively bonded to fiberglass-reinforced epoxy resin.
J Neural Eng
March 2025
Electrical and Computer Engineering, University of Tehran College of Engineering, North Kargar Street, Tehran, Tehran, Tehran, 1439957131, Iran (the Islamic Republic of).
Despite remarkable advances in EMG-based hand motor decoding, developing a practical and reliable decoder for robotic prosthetic hands remains unsolved. This study highlights inter-individual, inter-session, and intra-session variabilities of EMG signals as practical challenges and introduces a novel personalized and adaptive motor decoding framework, designed to mitigate their impact and improve hand motor decoding. A dataset was collected from twelve participants (8 male, 4 female), incorporating EMG signals from three forearm muscles during 20 repetitions of 9 distinct hand motions.
View Article and Find Full Text PDFStat Med
March 2025
Vaccine and Infectious Disease and Public Health Sciences Divisions, Fred Hutchinson Cancer Center, Seattle, Washington, USA.
Based on data from a randomized, controlled vaccine efficacy trial, this article develops statistical methods for assessing vaccine efficacy (VE) to prevent COVID-19 infections by a discrete set of genetic strains of SARS-CoV-2. Strain-specific VE adjusting for possibly time-varying covariates is estimated using augmented inverse probability weighting to address missing viral genotypes under a competing risks model that allows separate baseline hazards for different risk groups. Hypothesis tests are developed to assess whether the vaccine provides at least a specified level of VE against some viral genotypes and whether VE varies across genotypes.
View Article and Find Full Text PDFAdv Mater
March 2025
State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Institute of Fiber Materials and Devices, Department of Chemistry and Laboratory of Advanced Materials, Fudan University, Shanghai, 200438, China.
The rise of wearable electronics demands flexible energy storage solutions like flexible fiber energy storage devices (FESDs), known for their flexibility and portability. However, it remains difficult for existing fabrication methods (typically, finite-coating, thermal-drawing, and solution-extrusion) to simultaneously achieve desirable electrochemical performances and fast production of FESDs. Here, a new scalable coating-extrusion method is developed, utilizing a novel extruded spinneret with tapered apertures to create dual pressure zones.
View Article and Find Full Text PDFJ Chem Theory Comput
March 2025
Departamento de Física, Facultad de Ciencias, Universidad de Chile, Santiago Casilla 635, Chile.
The Fukui function and its associated potential serve as essential descriptors of chemical reactivity within the framework of conceptual density functional theory (c-DFT). While c-DFT is well-established for molecular systems, it encounters formal and technical challenges when applied to extended systems. This comprehensive study addresses the complexities involved in calculating the Fukui function and its potential in systems with periodic boundary conditions (PBC).
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