Automated high-throughput liquid handling operations in biolabs necessitate miniaturised and automatised equipment for effective space utilisation and system integration. This paper presents a thermal segment microwell plate control unit designed for enhanced microwell-based experimentation in liquid handling setups. The development of this device stems from the need to move towards geometry standardization and system integration of automated lab equipment. It incorporates features based on Smart Sensor and Sensor 4.0 concepts. An enzymatic activity assay is implemented with the developed device on a liquid handling station, allowing fast characterisation a high-throughput approach. The device outperforms other comparable devices in certain metrics based on automated liquid handling requirements and addresses the needs of future biolabs in automation, especially in high-throughput screening.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/d3lc00714f | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Retraction notice to "Air-liquid interface cultivation of Navicula incerta using hollow fiber membranes"[Chemosphere 307 (2022) 135625].
Chemosphere
December 2024
Zhejiang Provincial Key Laboratory for Subtropical Water Environment and Marine Biological Resources Protection, Wenzhou University, Wenzhou, China; Department of Chemical and Environmental Engineering, University of Nottingham Malaysia, B34, Semenyih, 43500, Selangor, Malaysia.
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/policies/article-withdrawal).
View Article and Find Full Text PDFComprehensive evaluation of sodium dichloroisocyanurate (NaDCC) tablets as a novel solid-state alternative to conventional membrane cleaning agents in gravity-driven filtration systems.
Chemosphere
December 2024
Department of Environmental Research, Korea Institute of Civil Engineering and Building Technology, Gorang-Daero 283, Ilsanseo-Gu, Goyang, Gyeonggi 10223, Republic of Korea; Department of Civil and Environment Engineering, University of Science and Technology (UST), 217 Gajeong-Ro, Yuseong-Gu, Daejeon, 34113, Republic of Korea. Electronic address:
Gravity-driven membrane (GDM) systems are increasingly recognized as sustainable and energy-efficient solutions for decentralized water treatment. However, membrane fouling, particularly by organic matter, remains a significant operational challenge, necessitating regular chemical cleaning to maintain performance. The present study was undertaken to investigate the cleaning efficiency of sodium dichloroisocyanurate (NaDCC) tablets, a novel solid-state alternative to conventional liquid cleaning agents such as sodium hypochlorite (NaOCl), sodium lauryl sulfate (SLS), acetic acid, and citric acid.
View Article and Find Full Text PDFPerformance of HPV Self-Sample Collected by a Novel Kit in Comparison with Clinician Collected Sample for Cervical Cancer Screening.
Asian Pac J Cancer Prev
December 2024
Department of Obstetrics and Gynaecology, Baroda Medical college and Sir Sayajirao General Hospital, Baroda, India.
Background And Objectives: We are reporting the performance of HPV self-sample collected by a novel kit in comparison with clinician collected cervical sample for HPV testing for cervical cancer screening.
Methods: Consenting, eligible women aged 25 to 60, with a positive cervical cancer screening test report in the past one year but without any prior treatment for cervical abnormalities were enrolled in the study. Each woman provided 2 samples for the HPV test (vaginal self-sample collected with the CERVICHECKTM, an indigenous kit from India and cervical sample collected by the clinician).
How to Convert a 3D Printer to Personal Automated Liquid Handler for Life Science Workflows.
SLAS Technol
December 2024
Center for Biomedical Engineering, School of Engineering, Brown University, Providence, RI 02912, USA. Electronic address:
Automated liquid handlers are fundamental in modern life science laboratories, yet their high costs and large footprints often limit accessibility for smaller labs. This study presents an innovative approach to decentralizing a liquid handling system by converting a low-cost 3D printer into a customizable and accurate liquid handler. The Personal Automated Liquid Handler (PALH) system, costing ∼$400, incorporates a single-channel pipet, custom 3D-printed components, and open-source software for personalized workflows, allowing researchers to build and modify the system for specific experimental needs.
View Article and Find Full Text PDFEvaluation of metabolite stability in dried blood spot stored at different temperatures and times.
Sci Rep
December 2024
Metanotitia Inc, Building C4, Science and Technology Innovation Headquarters, Shenzhen (Harbin) Industrial Park, 288 Zhigu Street, Songbei District, Harbin, 150029, China.
Dried blood spot (DBS) sampling offers significant advantages over conventional blood collection methods, such as reduced sample volume, minimal invasiveness, suitability for home-based sampling, and ease of transport. However, understanding the effects of variable storage temperatures and times on metabolite stability is crucial due to varying intervals and delivery conditions between sample collection and metabolomics analysis. To minimize biological variances, all samples were collected from the same individual simultaneously and stored at three different temperatures (4 °C, 25 °C, and 40 °C) for diverse time points (3, 7, 14, and 21 days).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!