Antioxidant and antiaging activities of and their combinations.

Aging is a natural skin process that occurs due to intrinsic and extrinsic factors, such as excessive exposure to ultraviolet light (photoaging). The mechanism of damage involves the production of excess free radicals that trigger oxidative stress in the skin. Determining the natural products that have high antioxidant activities as antiaging is important. and are typical Aceh plants that are believed to have high antioxidant effects. The aim of this study was to determining the contents of and as well as to determine the antioxidant and antiaging activities of either individually or combinations. The qualitative phytochemical and semi-quantitative analysis of the extracts were measured using gas chromatography-mass spectroscopy (GC-MS). The antioxidant activity was examined by radical scavenging using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical method while the antiaging activity was measured using the tyrosinase enzyme inhibition test. The phenolic and flavonoid contents of were higher than (66.34 vs 24.71 mg gallic acid equivalent/gr and 80.52 vs 60.20 mg quercetin equivalent/gr, respectively. The inhibitory concentration (IC50) of extract in inhibiting DPPH indicated that had a better antioxidant activity than . The combination of and extracts had a lower IC50 compared to alone. and extracts had a weak potential to inhibit tyrosinase activity (IC50 value ≥1000 μg/mL). In conclusion, this study indicates that and have strong antioxidant activities and these might associate with polyphenol contents.