AI Article Synopsis
- The review covers the pathophysiology, clinical features, diagnosis, and treatment options for Acanthamoeba keratitis (AK), highlighting its significant impact on eye health.
- Early diagnosis and prompt treatment are crucial for improving patient outcomes, as AK can often be misdiagnosed and may involve co-infections that complicate recovery.
- The primary treatment involves the use of biguanides and diamidines, with surgical intervention considered only if necessary.
Article Abstract
This is a comprehensive review after a thorough literature search in PubMed-indexed journals, incorporating current information on the pathophysiology, clinical features, diagnosis, medical and surgical therapy, as well as outcomes of Acanthamoeba keratitis (AK). AK is a significant cause of ocular morbidity, and early diagnosis with timely institution of appropriate therapy is the key to obtaining good outcomes. The varied presentations result in frequent misdiagnosis, and co-infections can increase the morbidity of the disease. The first line of therapy continues to be biguanides and diamidines, with surgery as a last resort.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11149514 | PMC |
| http://dx.doi.org/10.4103/IJO.IJO_2627_23 | DOI Listing |
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