The current study describes the chemical composition, antifungal, antibiofilm, antibacterial and molecular docking studies of growing in Malaysia. The essential oil was obtained through hydrodistillation and characterized using gas chromatography (GC-FID) and gas chromatography-mass spectrometry (GC-MS). The antifungal and antibacterial activities were developed using the broth microdilution assay, whereas the effect on the microbial biofilms was determined using a semi-quantitative static biofilm assay. A total of 31 components were identified, which represent 99.5 % of the essential oil. The results revealed that the essential oil consisted mainly of -pinene (15.6 %), -terpineol (13.3 %), -pinene (11.1 %), caryophyllene oxide (8.8 %), limonene (8.1 %), borneol (6.0 %) and viridiflorol (5.1 %). The results of the microdilution method showed that essential oil exhibited activity against and with minimal inhibitory concentration values of 125 and 250 μg/mL, respectively. Furthermore, essential oil decreased the biofilm of and by 20.11 ± 0.27 % and 32.10 ± 4.81 % when treated with 250 μg/mL. The best docking energy was observed with viridiflorol (-29.7 kJ/mol). This study highlights that essential oil can potentially be a natural antifungal, antibacterial, and antibiofilm agent that could be applied in the pharmaceutical and food industries.
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http://dx.doi.org/10.1515/znc-2023-0133 | DOI Listing |
Cell Mol Biol (Noisy-le-grand)
January 2025
Laboratory of Cellular Toxicology, Faculty of Science, Department of Biology, Badji Mokhtar University, Annaba, Algeria.
This study investigates the chemical composition of the essential oil (EO) extracted by hydrodistillation from dry Eucalyptus leaves (Eucalyptus globulus) and its antifungal, antibacterial and antioxidant potential. The Eucalyptus leaves were harvested in the commune of Seraïdi (north-eastern Algeria). Chemical analysis carried out by chromatography coupled with mass spectrophotometry (GC-SM) revealed the presence of 20 molecules representing approximately 100% of the overall component, with a yield of 1.
View Article and Find Full Text PDFPak J Pharm Sci
January 2025
Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan.
This study evaluated the antioxidant and antiproliferative effects of aqueous, ethanolic and methanolic extracts of Sedum nicaeense flowers and leaves. The MTT assay assessed cytotoxicity against colorectal cancer cells (Caco-2, HCT-116), breast cancer cells (T47D, MCF-7) and normal fibroblasts (MRC-5), while the ferric-reducing antioxidant power (FRAP) assay measured antioxidant capacity. Essential oils from flowers and leaves were analyzed using gas chromatography-mass spectrometry (GC-MS).
View Article and Find Full Text PDFSci Rep
January 2025
Department of Materials Science and Engineering, Faculty of Engineering, Arak University, Arak, 38156-8-8349, Iran.
Strawberry fruits are highly perishable and have a limited shelf life. Therefore, effective methods such as essential oils (EOs) and edible coatings are required to mitigate spoilage and maintain fruit quality during storage. In the current study, Echinophora platyloba EO was extracted and subsequently formulated into a nanoemulsion.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Biology, Faculty of Basic Sciences, Islamic Azad University, Shahrekord Branch, Shahrekord, Iran.
Controlling microbial pollutants is a significant public health concern as they cause several chronic microbial infections and illnesses. In recent years, essential oils (EOs) have become intriguing alternatives for synthetic antimicrobials due to their biodegradability, natural source extraction, and strong antibacterial properties. The bactericidal properties of alginate containing lemon essential oil were examined in this investigation.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Agro‑Environmental Sciences, Faculty of Agriculture, Kyushu University, 744 Motooka, Nishi‑ku, Fukuoka, 8190395, Japan.
Studies on the compounds of aromatic oils and their effects on psychophysiological changes in humans are often conducted separately. To obtain better validation, a suitable protocol is needed that can be extrapolated to large-scale olfactory stimulation experiments. Unfortunately, this type of study is still rarely performed.
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