Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1136/bmjebm-2024-112868 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Spatially Resolved Multiomics: Data Analysis from Monoomics to Multiomics.
BME Front
January 2024
CAS Key Lab of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China.
Spatial monoomics has been recognized as a powerful tool for exploring life sciences. Recently, spatial multiomics has advanced considerably, which could contribute to clarifying many biological issues. Spatial monoomics techniques in epigenomics, genomics, transcriptomics, proteomics, and metabolomics can enhance our understanding of biological functions and cellular identities by simultaneously measuring tissue structures and biomolecule levels.
View Article and Find Full Text PDFSOS2 phosphorylates FREE1 to regulate multi-vesicular body trafficking and vacuolar dynamics under salt stress.
Plant Cell
January 2025
State Key Laboratory of Plant Environmental Resilience, China Agricultural University, Beijing 100193, China.
Salt stress causes ion toxicity in plant cells and limits plant growth and crop productivity. Sodium ions (Na+) are transported out of the cell and sequestered in the vacuole for detoxification under salt stress. The salt excretion system is controlled by the SALT OVERLY SENSITIVE (SOS) pathway, which consists of the calcium sensors SOS3 and SOS3-LIKE CALCIUM BINDING PROTEIN 8, the protein kinase SOS2, and the plasma membrane Na+/H+ antiporter SOS1.
View Article and Find Full Text PDFCoaxial bioprinting of a three-layer vascular structure exhibiting blood-brain barrier function for neuroprotective drug screening.
Colloids Surf B Biointerfaces
January 2025
Centre for Advanced Jet Engineering Technology (CaJET), Key Laboratory of High-efficiency and Clean Mechanical Manufacture (Ministry of Education), National Experimental Teaching Demonstration Center for Mechanical Engineering (Shandong University), School of Mechanical Engineering, Shandong University, Jinan 250061, China.
The in vitro blood-brain barrier (BBB) structures can offer advantages for studying cerebrovascular functions and developing neuroprotective drugs. However, currently developed BBB models are overly simplistic and inadequate for replicating the complex three-dimensional architecture of the in vivo BBB. In this study, a method is introduced for fabricating a three-layer vascular structure exhibiting BBB function using a coaxial extrusion bioprinting technique with a two-layer nozzle.
View Article and Find Full Text PDFAbout the ozone ability in using adaptive chaos to restore a healthy state in the oxygen-ozone adjunct therapy.
Int Immunopharmacol
December 2024
Italian Scientific Society of Oxygen-Ozone Therapy (SIOOT) and High Master School of Oxygen-Ozone Therapy, University of Pavia, Italy.
The action of ozone in medicine is a subject of interest and lively, controversial debates. Its mechanisms of action are still far from fully understood. However, it is possible that ozone triggers a series of dynamics in living organisms related to chaos, multi-stable phenomena, and oscillatory processes.
View Article and Find Full Text PDFEvolution of Eligibility Criteria in Inflammatory Bowel Disease Clinical Trials: A Clinical Trial Databank Analysis.
United European Gastroenterol J
December 2024
Department of Gastroenterology and Hepatology, University Hospitals Leuven, Leuven, Belgium.
Background: Eligibility criteria in clinical trials have been criticised for being overly restrictive without clinical justification.
Objective: We aimed to investigate the types, evolution, and current status of eligibility criteria in clinical trials for inflammatory bowel diseases (IBD).
Methods: We performed a clinical trial databank search on clinicaltrials.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!