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http://dx.doi.org/10.36660/abc.20230819 | DOI Listing |
Nat Rev Cardiol
January 2025
Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.
Front Cardiovasc Med
December 2024
1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland.
Coronary artery disease (CAD)-cardiovascular condition occuring due to atherosclerotic plaque accumulation in the epicardial arteries-is responsible for disabilities of millions of people worldwide and remains the most common single cause of death. Inflammation is the primary pathological mechanism underlying CAD, since is involved in atherosclerotic plaque formation. Glucagon-like peptide-1 (GLP-1) is a peptide hormone which role extends beyond well-known carbohydrates metabolism.
View Article and Find Full Text PDFCardiovasc Res
December 2024
Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Oxidation of lipids, excessive cell death and iron deposition are prominent features of human atherosclerotic plaques. While extensive research has established the detrimental roles of lipid oxidation and apoptosis in atherosclerosis development, the involvement of iron in atherogenesis is not yet fully understood. With the emergence of an iron-dependent form of cell death termed ferroptosis, new attention has been brought to the complex interplay among iron, ferroptosis and atherosclerosis.
View Article and Find Full Text PDFCardiovasc Diabetol
December 2024
Cardiology Department, Beijing Anzhen Hospital, Anzhen Road No. 2, Chaoyang District, Beijing, China.
Background: Atherogenic index of plasma (AIP) has been recommended as a marker of plasma atherogenicity. The impact of AIP on plaque characteristics is not fully understood.
Purpose: The study investigates the relationship between AIP and coronary plaque features in patients with acute coronary syndrome (ACS).
Nutrients
November 2024
Laboratorio de Investigación en Obesidad y Diabetes, Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Guerrero, Chilpancingo de los Bravo 39087, Guerrero, Mexico.
Oxidized low-density lipoproteins (ox-LDLs) are involved in atherosclerotic plaque formation and progression and have been linked to insulin resistance (IR). Myeloperoxidase is a potent oxidant of lipoproteins related to atherogenic risk. High-density lipoproteins (HDLs) are considered antioxidants due to their association with paraoxonase 1 (PON1).
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