AI Article Synopsis
- The study aimed to evaluate how effective personalized dietary changes are for meeting nutritional needs in patients receiving hematopoietic stem cell transplantation (HSCT).
- It involved a pilot study where researchers assessed the nutritional status of 25 patients before and after HSCT, finding that while most were well-nourished initially, many experienced weight loss and decreased food intake during treatment.
- The findings highlighted that continuous dietary adjustments were crucial for maintaining nutrition, as symptoms like mucositis and nausea hindered food intake, with 52% of patients requiring additional oral nutritional support.
Article Abstract
Introduction: the objective of the study was to assess the efficacy of an individualized dietary adaptation to achieve nutritional requirements in patients undergoing hematopoietic stem cell transplantation (HSCT). Methodology: a pilot study of a nutritional intervention in patients undergoing HSCT. A nutritional assessment was performed the first 24 hours of admission and every 48-72 hours until discharge, or + 40 days after the transplant, making dietary adaptations. Results: 25 patients were recruited. According to MUST, 92.0 % (n = 23) were well nourished at the initial visit, with a loss of 2.1 (3.8) kg and a BMI of 26.4 kg/m2 (4.2). Before HSCT, there was already a decrease in intake of 15.4 (23.5) % and in body weight of 0.2 (3.2) kg; after the HSCT, the weight loss was 3.4 (5.0) kg and the decrease in intake was 6.5 (30.4) %. The predominant symptoms were mucositis (60 %), nausea (60 %), and diarrhea (44 %). The diet was adapted in 100 % of the patients, 52 % received oral nutritional support (ONS) (n = 13); enteral nutrition (EN) and parenteral nutrition (PN) were used only once. Conclusion: the nutritional status of patients undergoing HSCT is normal on admission but deteriorates during transplantation and prior conditioning. Dietary intervention is key to maintaining oral intake and reducing the risk of malnutrition.
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| http://dx.doi.org/10.20960/nh.04745 | DOI Listing |
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