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| http://dx.doi.org/10.4187/respcare.11748 | DOI Listing |
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Effects of Automated Versus Conventional Ventilation on Quality of Oxygenation-A Substudy of a Randomized Crossover Clinical Trial.
J Clin Med
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Department of Intensive Care, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
: Attaining adequate oxygenation in critically ill patients undergoing invasive ventilation necessitates intense monitoring through pulse oximetry (SpO) and frequent manual adjustments of ventilator settings like the fraction of inspired oxygen (FiO) and the level of positive end-expiratory pressure (PEEP). Our aim was to compare the quality of oxygenation with the use of automated ventilation provided by INTELLiVENT-Adaptive Support Ventilation (ASV) vs. ventilation that is not automated, i.
View Article and Find Full Text PDFThree-Level Nanoparticle Rocket Strategy for Colorectal Cancer Therapeutics in Photothermal Therapy, Inflammation Modulation, and Cuproptosis Induction.
Adv Healthc Mater
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Department of Oncology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China.
Disturbances in intracellular copper (Cu) homeostasis can trigger cuproptosis, a new form of cell death, which, when combined with photothermal therapy (PTT), offers a promising solution to the persistent challenges in colorectal cancer (CRC) treatment. In this study, a "three-level nanoparticle rocket" strategy is developed by engineering CuO, a multifunctional Cu-based nanoenzyme that is photothermal and has electron transfer properties and antioxidant efficiency. CuO effectively remodels the inflammatory environment by scavenging reactive oxygen species, thereby overcoming the traditional limitations of PTT.
View Article and Find Full Text PDFComparing multi-texture fibrosis analysis versus binary opacity-based abnormality detection for quantitative assessment of idiopathic pulmonary fibrosis.
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Department of Diagnostic and Interventional Radiology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Automated tools for quantification of idiopathic pulmonary fibrosis (IPF) can aid in ensuring reproducibility, however their complexity and costs can differ substantially. In this retrospective study, two automated tools were compared in 45 patients with biopsy proven (12/45) and imaging-based (33/45) IPF diagnosis (mean age 74 ± 9 years, 37 male) for quantification of pulmonary fibrosis in CT. First, a tool that identifies multiple characteristic lung texture features was applied to measure multi-texture fibrotic lung (MTFL) by combining the amount of ground glass, reticulation, and honeycombing.
View Article and Find Full Text PDFGuidelines for Accurate and Precise Stable Isotope Analysis of Calcite, Dolomite, and Magnesite Using a Carbonate Device for Continuous Flow-Isotope Ratio Mass Spectrometry (CF-IRMS).
Rapid Commun Mass Spectrom
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School of Earth, Environment & Society, McMaster University, Hamilton, Ontario, Canada.
Rationale: Carbonate minerals are one of the most popular samples for an automated sample preparation system for CF-IRMS, such as GasBench II and iso FLOW, but no standardized analytical protocols exist. This study gives guidelines on optimal analytic conditions for carbon and oxygen isotope analysis of Ca-Mg carbonates when using the carbonate-phosphoric acid reaction method.
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Creat Nurs
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Department of Pediatrics, Haeundae Paik Hospital, Inje University, Busan, South Korea.
This study aimed to compare the pain-related behavioral and physiological responses and puncture-related characteristics between automated and laser lancets and examine the correlation between infants' pain-related responses and facial expressions during heel lancing in a neonatal intensive care unit. Pain-related responses were assessed using the Neonatal Infant Pain Scale, heart rate, and oxygen saturation through pulse oximetry. Facial expressions were also analyzed using a facial recognition application.
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