[Salivary gland tumors: 2022 WHO blue book and beyond].

Ann Pathol

Service d'anatomie et cytologie pathologiques, University Hospital Centre Nantes, Nantes université, CHU de Nantes, 44000 Nantes, France; Inserm, INCIT, UMR 1302/EMR6001, CNRS, Immunology and New Concepts in ImmunoTherapy, Nantes, France. Electronic address:

Published: May 2024

AI Article Synopsis

  • * A new benign tumor, keratocystoma, was introduced, while sclerosing polycystic adenosis was reclassified as a tumoral entity and now termed sclerosing polycystic adenoma.
  • * Significant changes include doubts about oncocytic carcinoma's existence, the emergence of microsecretory and microcystic sclerosing adenocarcinomas as new malignant entities, and the recognition of primary mucinous adenocarcinoma as a distinct type.

Article Abstract

In 2022, the 5th edition of the WHO classification of Head and Neck tumors was published online. In the salivary gland chapter, a new benign entity, the keratocystoma, was introduced. The sclerosing polycystic adenosis has been recognized as tumoral and is now termed sclerosing polycystic adenoma. The striated duct adenoma now has its own dedicated chapter. Additionally, a new variant of pleomorphic adenoma, termed "canalicular adenoma-like," has been incorporated. Regarding malignant tumors of the salivary glands, significant doubts now exist regarding the actual existence of oncocytic carcinoma, which has been reclassified among emerging entities. Two new malignant entities have also emerged: microsecretory adenocarcinoma and microcystic sclerosing adenocarcinoma. Finally, primary mucinous adenocarcinoma of the salivary glands has been acknowledged as a distinct entity.

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Source
http://dx.doi.org/10.1016/j.annpat.2024.02.005DOI Listing

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