The coupling of diaziridines with donor-acceptor aziridines (DAAs) has been achieved using Zn-catalysis to furnish imidazopyrazole-4,4-dicarboxylates [1,4]-hydride shift. The use of Zn-catalysis, [1,4]-hydride shift, natural product modification and a late-stage molecular docking study are important practical features.

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http://dx.doi.org/10.1039/d4cc00226aDOI Listing

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