Objective: Hope is a malleable, cognitive, motivational skill that supports college student outcomes. We evaluated a college-level curriculum that taught hope skills.
Participants: Using a voluntary response sampling method, a total of 50 participants were included in the present study with 25 in each the control and intervention group.
Methods: All students completed surveys on hope at the beginning and end of the semester. The intervention group participated in a 10-week curriculum; students in the control group completed their regular introductory course.
Results: The intervention group had a significant increase in hope over the semester. Completing the hope course predicted significantly higher end-of- -semester hope, accounting for the beginning-of- semester hope.
Conclusions: Hope can be taught a classroom setting using a curriculum that requires limited financial and time resources. Improving college student hope has implications for their academic and well-being outcomes.
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http://dx.doi.org/10.1080/07448481.2024.2317189 | DOI Listing |
Front Oncol
January 2025
Sorbonne University and Saint-Antoine Hospital, APHP, Paris, France.
Background: Trifluridine/tipiracil (FTD/TPI) is approved as monotherapy and in combination with bevacizumab for the treatment of patients with refractory metastatic colorectal cancer (mCRC). FTD/TPI plus bevacizumab showed good tolerability in the phase 3 SOLSTICE (first-line) and SUNLIGHT (later-line) trials. This pooled analysis was performed to further characterize the safety of FTD/TPI plus bevacizumab and to compare safety in untreated and previously treated patients with mCRC.
View Article and Find Full Text PDFVienna Yearb Popul Res
September 2024
University of Minnesota, Minneapolis, Minnesota, USA.
Climate change is among the most urgent challenges of our time. While often considered a problem for the natural and physical sciences, the humanities and social sciences have made equally important interventions into research on the reciprocal relationship between humans and our climate. Because demography occupies the intersection of the natural and social sciences, and because it deals specifically with rates of change in social and natural processes, we believe it can make valuable contributions to the pressing imperatives of understanding and addressing climate change and mitigating the harms it is already visiting on the world's most vulnerable people.
View Article and Find Full Text PDFBMJ Oncol
May 2024
Institute of Cancer Policy, King's College London Faculty of Life Sciences & Medicine, London, UK.
The role of artificial intelligence (AI) in cancer care has evolved in the face of ageing population, workforce shortages and technological advancement. Despite recent uptake in AI research and adoption, the extent to which it improves quality, efficiency and equity of care beyond cancer diagnostics is uncertain to date. Henceforth, the objective of our systematic review is to assess the clinical readiness and deployability of AI through evaluation of prospective studies of AI in cancer care following diagnosis.
View Article and Find Full Text PDFJ Pharm Anal
January 2025
Research Center for Drug Metabolism, School of Life Sciences, Jilin University, Changchun, 130012, China.
Significant investment in nanocarrier drug delivery systems (Nano-DDSs) has yielded only a limited number of successfully marketed nanomedicines, highlighting a low rate of clinical translation. A primary contributing factor is the lack of foundational understanding of processes. Comprehensive knowledge of the pharmacokinetics of Nano-DDSs is essential for developing more efficacious nanomedicines and accurately evaluating their safety and associated risks.
View Article and Find Full Text PDFBMJ Oncol
January 2025
Department of Medicine, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, USA.
Objective: Cancer patients aged ≥80 years present unique characteristics affecting response to immune checkpoint inhibitors (ICIs), with unidentified molecular differences. This study aimed to explore potential biomarkers of response to ICI in patients ≥80 years.
Methods And Analysis: We analysed tumour samples (n=24 123) from patients ≥80 (versus<80) with non-small cell lung cancer (NSCLC), melanoma (MEL), and renal cell cancer (RCC).
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