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Rubisco is evolving for improved catalytic efficiency and CO assimilation in plants. | LitMetric

Rubisco is evolving for improved catalytic efficiency and CO assimilation in plants.

Proc Natl Acad Sci U S A

Department of Biology, University of Oxford, Oxford OX1 3RB, United Kingdom.

Published: March 2024

AI Article Synopsis

Article Abstract

Rubisco is the primary entry point for carbon into the biosphere. However, rubisco is widely regarded as inefficient leading many to question whether the enzyme can adapt to become a better catalyst. Through a phylogenetic investigation of the molecular and kinetic evolution of Form I rubisco we uncover the evolutionary trajectory of rubisco kinetic evolution in angiosperms. We show that is among the 1% of slowest-evolving genes and enzymes on Earth, accumulating one nucleotide substitution every 0.9 My and one amino acid mutation every 7.2 My. Despite this, rubisco catalysis has been continually evolving toward improved CO/O specificity, carboxylase turnover, and carboxylation efficiency. Consistent with this kinetic adaptation, increased rubisco evolution has led to a concomitant improvement in leaf-level CO assimilation. Thus, rubisco has been slowly but continually evolving toward improved catalytic efficiency and CO assimilation in plants.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10945770PMC
http://dx.doi.org/10.1073/pnas.2321050121DOI Listing

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