Explore & actuate: the future of personalized medicine in oncology through emerging technologies.

Curr Opin Oncol

UM-DAE Centre for Excellence in Basic Sciences, School of Biological Sciences, University of Mumbai, Kalina Campus, Mumbai, Maharashtra, India.

Published: March 2024

AI Article Synopsis

  • The future of medicine aims to personalize patient care through the integration of omics technologies, which can help address the unique challenges of cancer treatment.
  • Recent advancements in various omics technologies provide detailed molecular information, which is crucial for evaluating their potential application in clinical settings.
  • A new framework for assessing these technologies supports clinicians in choosing and combining tools effectively to improve personalized medicine approaches.

Article Abstract

Purpose Of Review: The future of medicine is aimed to equip the physician with tools to assess the individual health of the patient for the uniqueness of the disease that separates it from the rest. The integration of omics technologies into clinical practice, reviewed here, would open new avenues for addressing the spatial and temporal heterogeneity of cancer. The rising cancer burden patiently awaits the advent of such an approach to personalized medicine for routine clinical settings.

Recent Findings: To weigh the translational potential, multiple technologies were categorized based on the extractable information from the different types of samples used, to the various omic-levels of molecular information that each technology has been able to advance over the last 2 years. This review uses a multifaceted classification that helps to assess translational potential in a meaningful way toward clinical adaptation.

Summary: The importance of distinguishing technologies based on the flow of information from exploration to actuation puts forth a framework that allows the clinicians to better adapt a chosen technology or use them in combination to enhance their goals toward personalized medicine.

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Source
http://dx.doi.org/10.1097/CCO.0000000000001016DOI Listing

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