Larvicidal activity of three Eritrean medicinal plants was evaluated against by conducting the bioassay using WHO methods. Efficacy of the plant extracts of and was evaluated against 3rd instar larvae and mortality was recorded. LC and LC of the various plant extracts were also calculated using probit analysis. The morphological analysis of treated larvae was also performed. Extracts of and were prepared using different solvents viz chloroform, 70% ethanol and water. Of the screened extracts, the chloroform extracts of exhibited the highest larvicidal activities and has the minimum LC and LC (24 mg/ml and 198.411 mg/ml respectively). Chloroform extract of exhibited the least larvicidal activity with maximum LC and LC (736.883 mg/ml and 1188.699 mg/ml respectively). Microscopic analysis confirmed the changes in the larvae caused by various plants extracts. An accumulation of dark pigmentation was observed in abdominal region and in the anal papillae after contact and also showed major structural damage such as destruction of the gut.
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http://dx.doi.org/10.1007/s12639-024-01653-7 | DOI Listing |
Sci Rep
January 2025
Division of National Control of Communicable Diseases, Ministry of Health, Asmara, Eritrea.
Real-world data on treatment outcomes or the quality of large-scale chronic hepatitis B (CHB) treatment programs in sub-Saharan Africa (SSA) is extremely difficult to obtain. In this study, we aimed to provide data on the prevalence and incidence of mortality, loss to follow-up (LFTU), and their associated factors in patients with CHB in three treatment centres in Eritrea. Additional information includes baseline clinical profiles of CHB patients initiated on nucleos(t)ide analogue (NUCs) along with a comparison of treatment with Tenofovir disoproxil fumarate (TDF) vs.
View Article and Find Full Text PDFJ Med Case Rep
November 2024
Department of Internal Medicine, Wollo University, Dessie, Ethiopia.
Background: Charcot-Marie-Tooth disease is a spectrum of inherited disorders characterized by both motor and sensory manifestations, which include prominent distal muscle weakness, foot deformities (pes cavus and hammer toes), and sensory deficits. Postural tremor as a manifestation of Charcot-Marie-Tooth is seldom present, except in a variant of Charcot-Marie-Tooth subtype 1 (Roussy-Levy syndrome), and its presence often results in a diagnostic dilemma.
Case Presentation: We present a 34-year-old Eritrean man who came to our hospital with a complaint of tremors of the hands of 6 months duration.
HIV AIDS (Auckl)
November 2024
Department of Internal Medicine, Tessenay Hospital, Eritrean Ministry of Health Gash Barka Branch, Tessenai, Eritrea.
Background: In the landscape of HIV treatment, combined antiretroviral therapy (cART) is a cornerstone in managing viral loads and boosting CD4+ T-cell counts. Nevertheless, disparities in treatment outcomes remain persistent, and a subset of children fail to achieve adequate immunologic reconstitution (IR). This study aims to investigate the demographic and clinical factors associated with inadequate IR in HIV-infected children in Eritrea.
View Article and Find Full Text PDFAntimicrob Resist Infect Control
September 2024
Ministry of Health, Asmara, Eritrea.
Background: Despite their significant contribution to reducing mortality and morbidity from infectious diseases, antibiotics face challenges due to their inappropriate use, one of which is self-medication. This study assessed the prevalence of|| self-medication with antibiotics among Eritrean college students and its associated factors.
Methods: An analytical cross-sectional study evaluated the prevalence of self-medication with antibiotics among students from five colleges from September 2019 to February 2020.
Sci Rep
July 2024
Biostatistics and Epidemiology, Department of Statistics, College of Sciences, Mai-Nefhi, Eritrea.
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