Iliopsoas fibrosis after revision of total hip arthroplasty revealed by Ga-FAPI PET/CT: a case report.

Front Med (Lausanne)

Department of Sports Medicine, Peking University Third Hospital, Institute of Sports Medicine of Peking University, Beijing Key Laboratory of Sports Injuries, Beijing, China.

Published: February 2024

AI Article Synopsis

  • Total hip arthroplasty (THA) is an effective surgical procedure for pain relief and joint function improvement but can lead to complications like skeletal muscle fibrosis, which is often overlooked.
  • A 75-year-old man experienced persistent groin pain after a revision THA, and while standard tests were normal, a Ga-FAPI PET/CT scan revealed abnormal activity in the iliopsoas muscle, indicating fibrosis.
  • The findings suggest that the radiation uptake pattern from the scan may serve as a valuable diagnostic tool for skeletal muscle fibrosis post-THA.

Article Abstract

Background: Total hip arthroplasty (THA) is a well-established surgical procedure that has been extensively validated to alleviate pain, enhance joint function, improve the ability to perform daily activities, and enhance overall quality of life. However, this procedure is associated with certain complications, among which skeletal muscle fibrosis is a frequently overlooked but significant complication that can lead to persistent pain. Currently, there is no effective method for diagnosing skeletal muscle fibrosis following total hip arthroplasty.

Case Report: We report a 75-year-old male patient who complained of left groin pain after revision total hip arthroplasty. Serological examinations, X-rays, and bone scan results were all normal. However, during the Ga-FAPI PET/CT examination, we observed significant radiotracer uptake along the iliopsoas muscle. This abnormal uptake pattern suggested potential biological activity in this specific area. Combined with physical examination, the patient was diagnosed with iliopsoas fibrosis.

Conclusions: The presented images indicated that the uptake pattern was an important indicator for diagnosis, and the prospect of fibroblast activation protein in the diagnosis of skeletal muscle fibrosis has shown certain application value.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10909810PMC
http://dx.doi.org/10.3389/fmed.2024.1328630DOI Listing

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