Endogenous endophthalmitis represents an ophthalmological emergency requiring immediate diagnostics and treatment. Pathogens should be detected using appropriate methods, such as the Freiburg endophthalmitis set. In bacterial endophthalmitis both Gram-positive and Gram-negative bacteria can be detected. Frequent underlying sources include endocarditis, gastrointestinal or urogenital surgery, indwelling venous catheters, liver abscesses, skin or soft tissue infections, meningitis or less commonly, intravenous drug abuse. The treatment consists of systemic and intraocular administration of antibiotics and vitrectomy. Systemic or intraocular corticosteroids can additionally be considered.
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A rare case of Stenotrophomonas maltophilia endogenous endophthalmitis in pediatric age group.
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Background: We report a unique case of Stenotrophomonas maltophilia-related pediatric endogenous endophthalmitis.
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We identified Prototheca spp. microalga in ocular samples of a cat in Spain with nontreatable endogenous endophthalmitis. Within 2 years, the eye lesions progressively worsened and neurologic signs appeared, suggesting systemic spread of the infection.
View Article and Find Full Text PDFIntroduction: Infectious endophthalmitis, a vision-threatening disease caused by exogenous or endogenous microbial invasion, may require vitrectomy with or without silicone oil (SO) tamponade in severe cases. SO antimicrobial effects have been suggested but not demonstrated in an in vitro environment mimicking real clinical conditions. Using an in vitro intraocular tamponade model, we investigated the antimicrobial activity of SO against 11 bacterial and 1 fungal species, including antibiotic-resistant strains of Staphylococcus aureus and Klebsiella pneumoniae.
View Article and Find Full Text PDFEndogenous Endophthalmitis in the Setting of Kidney Disease: A Case Series.
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Blood stream infections (BSI) are common in patients with kidney disease. Metastatic foci of infections are one of the known complications of BSI. Endophthalmitis which is defined as infection and inflammation of the inner coats of the eye ball and intraocular fluids (aqueous and vitreous), is one such focus.
View Article and Find Full Text PDFBilateral Endogenous Endophthalmitis Secondary to Staphylococcus aureus Bacteremia.
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Bacterial endogenous endophthalmitis is caused by a breach of the blood-ocular barrier by pathogens originating from distant sites. It is a rare cause of endophthalmitis and can lead to devastating outcomes without prompt and adequate treatment. We report the case of a 50-year-old woman with a history of type II diabetes mellitus who experienced an episode of acute myocardial infarction complicated by an acute exacerbation of chronic kidney disease, catheter-related infection, bloodstream infection, bacterial endocarditis, and bilateral endogenous endophthalmitis confirmed by blood culture and bilateral vitreous culture showing growth of methicillin-sensitive (MSSA).
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