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Relationship of Biochemical and Sonographic Markers with Disease Severity in Rosacea Patients Without Cardiovascular Disease.
Life (Basel)
January 2025
Department of Dermatology, New York Medical College, New York, NY 10595, USA.
Rosacea is a chronic inflammatory skin disorder characterized by central facial redness, papulopustular lesions, and occasionally phymatous changes. There is ongoing debate regarding rosacea as a cutaneous disease with systemic inflammatory effects and its associations with cardiovascular diseases. Although the pathogenesis of both atherosclerosis and rosacea demonstrate notable similarities, particularly in the central role of inflammation, significant gaps in understanding these connections remain.
View Article and Find Full Text PDFCharacterization of Cutaneous Radiation Syndrome in a Mouse Model Using [18F]F- Fluorodeoxyglucose Positron Emission Tomography.
Health Phys
January 2025
Nuclear Medicine and Molecular Imaging Sciences Program, Department of Clinical & Diagnostic Sciences, School of Health Professions, University of Alabama at Birmingham, Birmingham, AL
Ionizing radiation on the skin has the potential to cause various sequelae affecting quality of life and even leading to death due to multi-system failure. The development of radiation dermatitis is attributed to oxidative damage to the skin's basal layer and alterations in immune response, leading to inflammation. Past studies have shown that [18F]F-2-fluoro-2-deoxyglucose positron emission tomography-computed tomography ([18F]F-FDG PET/CT) can be used effectively for the detection of inflammatory activity, especially in conditions like hidradenitis suppurativa, psoriasis, and early atherosclerosis.
View Article and Find Full Text PDFLifetime Attributable Risk in Mammography Screenings in Dubai: The Influence of Breast Thickness and Age on Radiation Exposure.
Diagnostics (Basel)
January 2025
Department of Physics, Faculty of Science, University Putra Malaysia, Serdang 43400, Malaysia.
This study investigated the lifetime attributable risk (LAR) of radiation-induced breast cancer from mammography screening in Dubai. It aimed to explore the relationship between breast thickness, patient age, and the associated radiation dose during mammographic examinations. A retrospective analysis was conducted on 2601 patients aged 40 to 69 across five screening facilities in Dubai's healthcare system.
View Article and Find Full Text PDFIn vivo efficacy of a stabilized Vitamin C-based serum at pH 6 on some ageing facial signs of women of different ages and phototypes.
Int J Cosmet Sci
January 2025
L'Oréal Research & Innovation, Chevilly-Larue, France.
Objective: To assess, clinically and instrumentally, the efficacy of a stabilized 12% Vitamin C (VC)-based serum (pH 6) on skin photoageing of women of various age and phototype.
Materials And Methods: Eighty women, with Phototypes I to VI, of various age (45-70y) living in Mauritius, participated in an open, uncontrolled study. After a two-week period of washout, they applied the Vitamin C-based serum twice a day for 2 months onto their whole face as well as a hydrating cream every evening to ensure a comparable skin hydration level in all subjects.
Mesenchymal Stem Cell Extract Promotes Skin Wound Healing.
Int J Mol Sci
December 2024
Department of Oral Anatomy, Osaka Dental University, Osaka 573-1121, Japan.
Recently, it has been reported that mesenchymal stem cell (MSC)-derived humoral factors promote skin wound healing. As these humoral factors are transiently stored in cytoplasm, we collected them as part of the cell extracts from MSCs (MSC-ext). This study aimed to investigate the effects of MSC-ext on skin wound healing.
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