Comparison of bacteremic pneumonia caused by and : A retrospective study.

Saudi Med J

From the Second Affiliated Hospital (Li, Zhu, Zheng, Fang, Hu), Jiangxi Medical College, Nanchang University; from the Department of Jiangxi Provincial Key Laboratory of Medicine (Li, Zheng, Hu), Clinical Laboratory of the Second Affiliated Hospital of Nanchang University; and from the Department of Nursing (Xiong), the Second Affiliated Hospital of Nanchang University, Jiangxi, China.

Published: March 2024

AI Article Synopsis

  • The study aimed to compare the outcomes of patients with bacteremic pneumonia caused by different pathogens over a period from 2016 to 2019.
  • A total of 162 patients were analyzed, revealing a 30-day mortality rate of 43.75% for the KP-BP group compared to 21.95% for the -BP group, indicating significant differences in prognosis.
  • The research found that KP-BP patients faced higher mortality risks under certain conditions like being in intensive care or having resistant infections, whereas the Pitt bacteremia score was a key predictor of mortality for patients in the -BP group.

Article Abstract

Objectives: To compare the prognosis of bacteremic pneumonia caused by () and () pathogens.

Methods: A retrospective analysis was carried out on the clinical data of 162 patients who were diagnosed with bacterial pneumonia caused by either or between 2016-2019. The primary outcome of the analysis was the patients' 30-day mortality rate.

Results: There were 82 patients in the bacteremic pneumonia (-BP) group and 80 patients in the bacteremic pneumonia (KP-BP) group. The 30-day mortality rate was 43.75% (n=35/80) in the KP-BP group and 21.95% (n=18/82) in the -BP group (<0.001). Following the adjustment for confounding variables in 4 distinct models, the hazard ratios for the primary outcome in KP-BP were determined to be 0.70 (95% confidence interval [CI]: [0.44-1.02]) in Model 1, 0.72 (95% CI: [0.46-1.14]) in Model 2, 0.99 (95% CI: [0.57-1.73]) in Model 3, and 1.22 (95% CI: [0.69-2.18]) in Model 4.

Conclusion: Patients diagnosed with KP-BP exhibited a similar prognosis as those diagnosed with -BP. For patients with KP-BP, the risk of mortality was significantly higher for those who were in the intensive care unit, were infected with carbapenem-resistant strains, or had a high sequential organ failure assessment score. In patients with -BP, the Pitt bacteremia score was strongly associated with the 30-day mortality rate.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11115389PMC
http://dx.doi.org/10.15537/smj.2024.45.3.20230428DOI Listing

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