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Efficacy of Ceftazidime-avibactam in treating Gram-negative infections: a systematic review and meta-analysis.
Eur J Clin Microbiol Infect Dis
January 2025
University of Sassari, Sassari, Italy.
Introduction: Ceftazidime-avibactam (CAZ-AVI) has emerged as a promising treatment option for Gram-negative infections, particularly those caused by CAZ-Non-Susceptible (NS) pathogens. This systematic review and meta-analysis aim to assess the efficacy and safety of CAZ-AVI in these challenging infections.
Methods: We systematically queried EMBASE, Cochrane CENTRAL, and PubMed/Medline for studies published until September 15, 2024.
A rapid literature review of the impact of penicillin allergy on antibiotic resistance.
JAC Antimicrob Resist
February 2025
Department of Microbiology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Background: Antimicrobial resistance (AMR) is caused by the use and misuse of antibiotics. AMR is a global health concern, to which penicillin allergy (penA) labels appear to contribute. Patients who have penA labels are treated with non-penicillin antibiotics and receive more antibiotics when compared with patients without penA.
View Article and Find Full Text PDFAntimicrobial prescribing quality in Australian emergency departments: an analysis of the Hospital NAPS data set.
Antimicrob Steward Healthc Epidemiol
January 2025
Melbourne Medical School, University of Melbourne, Melbourne, VIC, Australia.
Objective: To analyze antimicrobial prescribing practices in Australian emergency departments (ED), identifying prescribing areas requiring improvement. This aims to inform antimicrobial stewardship (AMS) strategies to enhance antimicrobial prescribing quality.
Design: Retrospective analysis of the Hospital National Antimicrobial Prescribing Survey (NAPS) data set.
Developing a curriculum on antimicrobial stewardship for pediatric residents: a needs assessment.
Antimicrob Steward Healthc Epidemiol
January 2025
Department of Pediatrics, Division of Pediatric Critical Care Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Objective: Identify essential components of a curriculum on antimicrobial stewardship (AS) for pediatric residents.
Design: Survey.
Setting: Academic tertiary care children's hospital.
Development and validation of an antibiotic appropriateness metric for urinary tract infections and pyelonephritis in ambulatory settings.
Antimicrob Steward Healthc Epidemiol
January 2025
Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, NE, USA.
Ambulatory antibiotic stewardship has traditionally focused on acute respiratory infections with few studies evaluating metrics for other commonly encountered ambulatory conditions, including urinary tract infections (UTI). We describe the development and validation of an electronically captured appropriate antibiotic use metric for ambulatory UTIs using coding data.
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