It is a known fact that gastrointestinal diseases are extremely common among the public. The most common of these diseases are gastritis, reflux, and dyspepsia. Since the symptoms of these diseases are similar, diagnosis can often be confused. Therefore, it is of great importance to make these diagnoses faster and more accurate by using computer-aided systems. Therefore, in this article, a new artificial intelligence-based hybrid method was developed to classify images with high accuracy of anatomical landmarks that cause gastrointestinal diseases, pathological findings and polyps removed during endoscopy, which usually cause cancer. In the proposed method, firstly trained InceptionV3 and MobileNetV2 architectures are used and feature extraction is performed with these two architectures. Then, the features obtained from InceptionV3 and MobileNetV2 architectures are merged. Thanks to this merging process, different features belonging to the same images were brought together. However, these features contain irrelevant and redundant features that may have a negative impact on classification performance. Therefore, Dandelion Optimizer (DO), one of the most recent metaheuristic optimization algorithms, was used as a feature selector to select the appropriate features to improve the classification performance and support vector machine (SVM) was used as a classifier. In the experimental study, the proposed method was also compared with different convolutional neural network (CNN) models and it was found that the proposed method achieved better results. The accuracy value obtained in the proposed model is 93.88%.
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http://dx.doi.org/10.7717/peerj-cs.1919 | DOI Listing |
Biomol Biomed
December 2024
Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Severe acute pancreatitis (SAP) is one of the leading causes of hospital admissions for gastrointestinal diseases, with a rising incidence worldwide. Intestinal microbiota dysbiosis caused by SAP exacerbates systemic inflammatory response syndrome and organ dysfunction. Fecal microbiota transplantation (FMT) has emerged as a promising therapeutic option for gastrointestinal diseases.
View Article and Find Full Text PDFInt J Surg
January 2025
Department of Surgical Oncology, Fourth Affiliated Hospital of China Medical University.
Background: Several autoimmune diseases (ADs) are considered risk factors for gastrointestinal (GI) cancers. This study pooled and appraised the evidence associating ADs to GI cancer risks.
Methods: Three databases were examined from initiation through 26 January 2024.
N4-acetylcytidine (ac4C) modification is a crucial RNA modification widely present in eukaryotic RNA. Previous studies have demonstrated that ac4C plays a pivotal role in viral infections. Despite numerous studies highlighting the strong correlation between ac4C modification and cancer progression, its detailed roles and molecular mechanisms in normal physiological processes and cancer progression remain incompletely understood.
View Article and Find Full Text PDFBiosci Microbiota Food Health
August 2024
Department of Food Science, Széchenyi István University, Mosonmagyaróvár, 9200, Hungary.
The global probiotics market has been continuously growing, driven by consumer demand for immune-enhancing functional foods, dietary supplements, and natural therapeutics for gastrointestinal and gut function-mediated diseases. Probiotic microorganisms represent a diverse group of strains with complex but generalized mechanistic patterns. This review describes the various immunomodulatory mechanisms by which probiotics exert their effects, including the competitive exclusion of pathogenic microbes, production of antimicrobial substances, modulation of the immune system, and improvement of gut barrier function.
View Article and Find Full Text PDFFront Vet Sci
December 2024
Faculty of Veterinary Medicine, Veterinary Teaching Hospital, University of Lisbon, Lisbon, Portugal.
Background: A resting cortisol concentration (RC) higher than 2.0 μg/dL (55 nmol/L) is commonly used to rule out hypoadrenocorticism (HA). However, there is a significant overlap of RC between dogs with HA and those with other diseases.
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