Dysbiosis among oral microbial community in the oral cavity can lead to several oral diseases. Probiotic therapy is known to correct these imbalances. is one of the most studied strains of probiotics and can control oral microbiota through reuterin, a wide-spectrum antimicrobial agent. The objective of this review was to evaluate the effect of the antimicrobial activity of on the oral bacteria of humans. This review used PubMed, Scopus, EMBASE, ScienceDirect, and Google Scholar databases as bibliographic resources. Studies with matching keywords were analyzed and screened with PRISMA-ScR recommendations. Sixteen articles were selected for this review, which included a total of 832 patients. Based on this review, has a strong antibacterial effect against in healthy individuals but is not effective against Additionally, it has a significant antibacterial effect against in patients with periodontitis, although its effectiveness is not stable in patients with peri-implant infections. Furthermore, has varying results against other bacteria, indicating the need for further extensive research to ensure its efficacy.
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| http://dx.doi.org/10.12688/f1000research.139697.1 | DOI Listing |
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