Pharmaceutical managers have been encouraged to look to acquisitions and alliances for innovation. However, the literature warns that the capacity of a company to 'absorb' new knowledge is limited. Here, we introduce corporate divestitures as a tool for freeing up managerial attention. We build a sample of 349 companies, which announced 1784 divestitures and filed 63523 patents, over a 15-year period. We show that innovating companies that divest more produce more and improved patents, and those that divest to create corporate focus also produce more breakthroughs. In doing so, we introduce divestitures as an innovation tool, highlight the importance of the absorptive capacity of a company when discussing innovation, and add nuance to the discussion on external tools for innovation.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.drudis.2024.103937 | DOI Listing |
Nat Med
January 2025
Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Long-term risks of gene therapy are not fully understood. In this study, we evaluated safety outcomes in 783 patients over more than 2,200 total patient-years of observation from 38 T cell therapy trials. The trials employed integrating gammaretroviral or lentiviral vectors to deliver engineered receptors to target HIV-1 infection or cancer.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Zhongyuan Critical Metals Laboratory, Zhengzhou University, Zhengzhou 450001, China; The Key Lab of Critical Metals Minerals Supernormal Enrichment and Extraction, Ministry of Education, Zhengzhou 450001, China; School of Chemical Engineering, Zhengzhou University, Zhengzhou 450001, China; Luoyang Industrial Technology Institute, Luoyang 471000, China. Electronic address:
A magnetic chitosan-based ion-imprinted polymer (IIP) with high adsorption capacity, excellent selectivity for Ga(III), easy magnetic separation, and remarkable reusability was synthesized via a simple crosslinking polymerization. The IIP exhibited a Ga(III) adsorption capacity of 434.00 mg/g at pH 4, demonstrating high efficiency for Ga(III) removal from aqueous solutions.
View Article and Find Full Text PDFLancet Diabetes Endocrinol
January 2025
Division of Diabetes & Nutritional Sciences, School of Cardiovascular and Metabolic Medicine & Sciences, King's College London, London, UK; Catholic University of the Sacred Heart, Rome, Italy; University Polyclinic Foundation Agostino Gemelli IRCCS, Rome, Italy.
Small Methods
January 2025
BCMaterials, Basque Centre for Materials, Applications and Nanostructures; UPV/EHU Science Park, Leioa, 48940, Spain.
Carbon coating on SiO surface is crucial for enhancing initial Coulombic efficiency (ICE) and cycling performance in batteries, while also buffering volume expansion. Despite its market prevalence, the effects of the carbon layer's quality and structure on the electrochemical properties of SiO remain underexplored. This study compares carbon layers produced via gas-phase and solid-phase coating methods, introducing an innovative technique that sequentially uses two gases to develop a low-impedance hybrid carbon structure.
View Article and Find Full Text PDFJ Craniofac Surg
November 2024
Consultant ENT, Ministry of Health, Juba Teaching Hospital, Juba, South Sudan.
Introduction: Few patients in South Sudan have access to cleft lip repair due to limitations in health care facilities, personnel and road infrastructure. Samaritan's Purse is a non-governmental organization that provides chartered flights from road inaccessible regions to a single central hospital in this nation's capital. This study's purpose was to describe the chartered flight model for conducting nationwide cleft lip mission trips.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!