The orosensory features of alcoholic drinks are potent relapse triggers because they acquire incentive properties during consumption, including enhanced palatability. Whether mice similarly perceive alcoholic drinks to be more palatable after repeated consumption is complicated by reports showing that alcohol elicits aversive taste reactivity responses and conditions flavor avoidance. Here, by analyzing the microstructure of alcohol consumption, we report a gradual increase in lick bout duration relative to water that is partially maintained by an alcohol-paired flavor in extinction. We interpret lick bout duration to reflect an increase in the palatability alcohol and an alcohol-paired flavor. This finding demonstrates that bout duration is amenable to Pavlovian conditioning and highlights the importance of considering the microstructure of alcohol consumption in preclinical models of alcohol misuse.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.physbeh.2024.114500 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Insights into adult worker foraging dynamics within a Bombus terrestris (Hymenoptera: Apidae) colony.
J Econ Entomol
December 2024
State Key Laboratory of Resource Insects, Institute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing, China.
Bombus terrestris, an important eusocial insect, plays a vital role in providing pollination services for both wild plants and greenhouse crops. For the development of the colonies, the workers must leave the hives to collect nectar and pollen. However, limited findings about the foraging behavior of B.
View Article and Find Full Text PDFSedentary behaviors negatively related to depressive symptoms in college students:The roles of type and duration of sedentary behaviors.
Physiol Behav
December 2024
Department of Physical Education, Shanghai Jiao Tong University, Shanghai, China. Electronic address:
Objective: This study aimed to examine the associations between different types and duration of sedentary behaviors and depressive symptoms among college students.
Methods: A cross-sectional study was conducted at a university in Shanghai, China, utilizing convenience sampling to recruit 3,190 participants (mean age 20.06 ± 1.
Impact of electrical muscle stimulation-induced muscle contractions on endogenous pain modulatory system: a quantitative sensory testing evaluation.
BMC Musculoskelet Disord
December 2024
Faculty of Rehabilitation, Kobe Gakuin University, 518 Arise, Ikawadani-cho, Nishi-ku, Kobe, Hyogo, 651-2180, Japan.
Background: Exercise-induced hypoalgesia (EIH) is characterized by a reduction in pain perception and sensitivity across both exercising and non-exercising body parts during and after a single bout of exercise. EIH is mediated through central and peripheral mechanisms; however, the specific effect of muscle contraction alone on EIH remains unclear. Moreover, previous studies on electrical muscle stimulation (EMS) have primarily focused on local analgesic effects, often relying on subjective pain reports.
View Article and Find Full Text PDFObjectively-Measured Sedentary Time and Self-Reported Prescription Medication Use Among Adults: A Pilot Study.
Pharmacy (Basel)
December 2024
Department of Clinical and Applied Movement Sciences, Brooks College of Health, University of North Florida, Jacksonville, FL 32224, USA.
While previous research has linked physical activity (PA) with lower prescription medication consumption, limited evidence has investigated sedentary time (ST) as a major contributor to medication use, despite ST's known association with chronic disease and mortality risk, even when PA volume is considered. This study aimed to examine the independent associations between objectively measured ST, patterns of sedentary bouts, and self-reported prescription medication use among adults ≥25 years of age. Thirty-two participants reported the number and type of medications they were currently prescribed and wore an accelerometer continuously on their hip for seven days to detect their ST.
View Article and Find Full Text PDFInternational society of sports nutrition position stand: β-hydroxy-β-methylbutyrate (HMB).
J Int Soc Sports Nutr
December 2025
Nova Southeastern University, Department of Health and Human Performance, Davie, FL, USA.
Position Statement: The International Society of Sports Nutrition (ISSN) bases the following position stand on an analysis of the literature regarding the effects of β-Hydroxy-β-Methylbutyrate (HMB). The following 12 points have been approved by the Research Committee of the Society: 1. HMB is a metabolite of the amino acid leucine that is naturally produced in both humans and other animals.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!