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The diagnostic value of endoscopic ultrasound for esophageal subepithelial lesions: A review.
Medicine (Baltimore)
November 2024
Department of Thoracic Surgery, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Article Synopsis
- Esophageal subepithelial lesions (ESELs) include a range of tumors and diseases, such as leiomyomas and hemangiomas, often going undetected due to asymptomatic presentations.
- Common imaging methods for ESEL diagnosis involve conventional endoscopy, spiral computed tomography, and endoscopic ultrasound (EUS), with EUS being the most accurate.
- Recent advancements in EUS technology, including artificial intelligence and enhanced imaging techniques, have improved diagnostic accuracy for ESELs and helped reduce missed cases.
Rapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing.
Allergol Select
October 2024
Center for Child and Adolescent Health, Helios Hospital Krefeld, Academic Hospital of RWTH Aachen, Krefeld.
Article Synopsis
- Primary atopic disorders (PAD) are rare genetic conditions caused by specific gene variants that affect skin and immune function, making diagnosis challenging among common allergic disease cases.
- Identifying PAD requires recognizing clinical red flags like family history and unusual infections, as conventional lab tests are inadequate for definitive diagnosis.
- Whole-genome sequencing (WGS) enhances diagnostic efficiency and accuracy, but requires careful interpretation and collaboration among specialists to effectively manage PAD cases.
Heterogeneous Profile of ROR1 Protein Expression across Tumor Types.
Cancers (Basel)
May 2024
Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
The Wnt receptor ROR1 has generated increased interest as a cancer therapeutic target. Research on several therapeutic approaches involving this receptor is ongoing; however, ROR1 tissue expression remains understudied. We performed an immunohistochemistry analysis of ROR1 protein expression in a large cohort of multiple tumor and histologic types.
View Article and Find Full Text PDFLeiomyosarcoma of the esophagus, arising from lamina muscularis mucosae, in a combination with microinvasive squamous cell carcinoma-A case report.
Indian J Pathol Microbiol
May 2024
Department of General and Clinical Pathology, Medical University - Plovdiv, Plovdiv, Bulgaria.
Leiomyosarcoma of the esophagus is a very rare disease, accounting for less than 0.5% of malignant esophageal tumors. Esophageal leiomyosarcoma combined with squamous cell carcinoma is even rarer than solitary leiomyosarcoma.
View Article and Find Full Text PDFCarcinosarcoma of the Esophagus-A Diagnostic Challenge.
Ochsner J
January 2023
Department of Surgical Gastroenterology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Esophageal carcinosarcoma is an uncommon histologic variant of esophageal malignancy, occurring in approximately 0.5% to 2.8% of patients.
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