AI Article Synopsis
- Large burns cause significant changes in the body, but survival rates have improved due to better critical care and early treatment methods.
- Healing large burn wounds is still difficult because of limited donor skin, slow healing, and weakened immune systems.
- Combining skin substitutes and new grafting techniques can lead to better healing outcomes, and it’s important to discuss care goals with patients who might have a poor prognosis.
Article Abstract
Large burns provoke profound pathophysiological changes. Survival rates of patients with large burns have improved significantly with the advancement of critical care and adaptation of early excision protocols. Nevertheless, care of large burn wounds remains challenging secondary to limited donor sites, prolonged time to wound closure, and immunosuppression. The development of skin substitutes and new grafting techniques decreased time to wound closure. Individually, these methods have limited success, but a combination of them may yield more successful outcomes. Early identification of patients with likely poor prognosis should prompt goals of care discussion and involvement of a palliative care team when possible.
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| http://dx.doi.org/10.1016/j.cps.2023.11.007 | DOI Listing |
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