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Transcranial direct current stimulation (tDCS) in psychiatric disorders in early childhood (aged under 10 years): a systematic review.
Eur Child Adolesc Psychiatry
January 2025
Department of Psychiatry, Neurology, Psychotherapy and Psychosomatics in Childhood and Adolescence, Rostock University Medical Center, Gehlsheimer Straße 20, 18147, Rostock, Germany.
Transcranial direct current stimulation (tDCS) remains experimental for many psychiatric disorders in adults. Particularly in childhood, there is limited research on the evidence for the efficacy and mechanisms of action of tDCS on the developing brain. The objective of this review is to identify published experimental studies to examine the efficacy and mechanisms of tDCS in children with psychiatric or developmental disorders in early (prepubertal) childhood (aged under 10 years).
View Article and Find Full Text PDFThe effects of transcranial direct current stimulation on global cognition in patients with Alzheimer's disease: An update meta-analysis.
J Alzheimers Dis
January 2025
School of Clinical Medicine, Qilu Medical University, Zibo, Shandong, China.
Background: Alzheimer's disease (AD) is a neurodegenerative disease. At present, there are currently no drugs that can cure AD.
Objective: A number of empirical studies have shown that transcranial direct current stimulation (tDCS) may be used to treat cognitive abnormalities in patients with AD.
Efficacy and sustainability of 40 Hz high‐definition transcranial alternating current stimulation (tACS) in the treatment of sleep disturbances in mild neurocognitive disorders due to Alzheimer’s disease.
Alzheimers Dement
December 2024
The Chinese University of Hong Kong, Hong Kong, Hong Kong, Hong Kong
Background: To investigate the effects of 40 Hz high‐definition transcranial alternating current stimulation (HD‐tACS) on subjective sleep quality and domain‐specific cognitive functions in mild neurocognitive disorders due to Alzheimer’s disease (NCD‐AD).
Method: This study was a double blind, sham‐controlled randomized clinical trial. Ninety‐nine mild NCD‐AD patients were randomly assigned to receive a 4‐week course treatment of either 40 Hz HD‐tACS, HD transcranial direct current stimulation (HD‐tDCS), or sham transcranial current stimulation (HD‐tCS).
Efficacy of Transcranial Alternating Current Stimulation (tACS) in Cognition and Memory in Patients with Mild Cognitive Impairement or Alzheimer’s Disease. A Systematic Review and Meta‐analysis of Randomized Controlled Trials.
Alzheimers Dement
December 2024
Applied Medical Sciences, Misr University for Science and Technology, Cairo, Egypt
Background: Gamma desynchronization is an early pathophysiological event in Alzheimer’s disease with a disturbance in oscillation in the gamma frequency range 30‐80 Hz. This disruption was found to be directly related to the disease progression and severity. Thus, the use of transcranial alternating current stimulation (tACS) possessed greater interest.
View Article and Find Full Text PDFHome‐Based Multifocal Brain Circuit‐Based Neuromodulation Combining tACS and tDCS in Older Adults with Alzheimer’s Disease.
Alzheimers Dement
December 2024
Hinda and Arthur Marcus Institute for Aging Research at Hebrew SeniorLife, Boston, MA, USA
Background: Alzheimer’s disease (AD) affects over 55 million people worldwide and is characterized by abnormal deposition of amyloid‐β and tau in the brain causing neuronal damage and disrupting transmission within brain circuits. Episodic memory loss, executive deficits, and depression are common symptoms arising from altered function in spatially distinct brain circuits that greatly contribute to disability. Transcranial electrical stimulation (tES) can target these circuits and has shown promise to relieve specific symptoms.
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